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Plaque Registration and Event Detection In Computed Tomography (PREDICT)

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified March 2013 by Hiroshima University.
Recruitment status was:  Active, not recruiting
Information provided by (Responsible Party):
Yasuki Kihara, Hiroshima University Identifier:
First received: October 7, 2009
Last updated: March 18, 2013
Last verified: March 2013

October 7, 2009
March 18, 2013
October 2009
December 2012   (Final data collection date for primary outcome measure)
  • Major cardiac events (Cardiac death and acute coronary syndrome) [ Time Frame: 2 years after the CT-scan ]
  • All-cause death [ Time Frame: 2 years after the CT-scan ]
  • All-cause death [ Time Frame: 2 years after the CT-scan ]
  • Major cardiovascular events (Cardiovascular death, non-fatal MI, heart failure requiring hospitalization, or any stroke) [ Time Frame: 2 years after the CT-scan ]
Complete list of historical versions of study NCT00991835 on Archive Site
  • All coronary events (Cardiac death, non-fatal MI, unstable angina requiring hospitalization, late coronary revascularizations) [ Time Frame: 2 years after CT-scan ]
  • All cardiovascular events (Death, acute coronary syndrome, heart failure, cerebral disease, peripheral artery disease, aortic disease, and renal failure) [ Time Frame: 2 years after the CT-scan ]
The impact of statin on the changes in coronary plaque characteristics [ Time Frame: 2 years after CT-scan ]
Coronary plaque progression and managements for serum cholesterol, blood glucose, renal function and blood pressure: Especially impacts of statin on the changes in coronary plaque characteristics [ Time Frame: 2 years after CT ]
Not Provided
Plaque Registration and Event Detection In Computed Tomography
Prospective Multicenter Study to Investigate the Relationship Between the Characteristics of Coronary Artery Plaques and Cardiovascular Events Using Multidetector Computed Tomography Coronary Angiography
Disruption of an atherosclerotic plaque is responsible for at least two-thirds of acute coronary syndrome. Thus, identification of plaques vulnerable to rupture has become important. The natural history of individual plaques is unknown and needs to be established. Multidetector computed tomography (MDCT) angiography is a useful noninvasive imaging modality for assessing coronary plaque characteristics. Using MDCT, the researchers prospectively investigate the relationship between the characterization of coronary plaques and cardiovascular events in a large multicenter study.
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Observational Model: Cohort
Time Perspective: Prospective
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Probability Sample
patients reffered to cardiovascular hospital
  • Atherosclerosis
  • Cardiovascular Diseases
  • Coronary Artery Disease
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Yamamoto H, Awai K, Kuribayashi S, Kihara Y; PREDICT Investigators.. Rationale and design of the PREDICT (Plaque Registration and Evaluation Detected In Computed Tomography) registry. J Cardiovasc Comput Tomogr. 2014 Mar-Apr;8(2):90-6. doi: 10.1016/j.jcct.2013.12.004. Epub 2014 Jan 8.

*   Includes publications given by the data provider as well as publications identified by Identifier (NCT Number) in Medline.
Unknown status
December 2014
December 2012   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • patients with known or suspected coronary artery disease.

Exclusion Criteria:

  • irregular heart beat,
  • known allergy towards the contrast agent,
  • renal dysfunction,
  • uncontrolled heart failure,
  • previous coronary bypass surgery, or pacemaker or ICD implantation, ST elevation MI or unstable hemodynamic condition,
  • impossible breath-hold, OR
  • end-stage cancer.
Sexes Eligible for Study: All
20 Years and older   (Adult, Senior)
Contact information is only displayed when the study is recruiting subjects
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Yasuki Kihara, Hiroshima University
Hiroshima University
Not Provided
Study Chair: Yasuki Kihara, MD,PhD Hiroshima University
Hiroshima University
March 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP