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Muscle Glycogen Synthesis When Caffeine and Protein is Co-Ingested With Carbohydrates

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Milou Beelen, Maastricht University Medical Center
ClinicalTrials.gov Identifier:
NCT00975390
First received: September 10, 2009
Last updated: April 13, 2015
Last verified: April 2015

September 10, 2009
April 13, 2015
February 2009
September 2009   (final data collection date for primary outcome measure)
Muscle glycogen synthesis rates [ Time Frame: 6 hours ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT00975390 on ClinicalTrials.gov Archive Site
Glycogen synthase activity, plasma glucose, insulin, free fatty acids and epinephrine responses [ Time Frame: 6 hours ] [ Designated as safety issue: No ]
Same as current
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Muscle Glycogen Synthesis When Caffeine and Protein is Co-Ingested With Carbohydrates
The Effect of Caffeine or Protein Co-ingestion With Carbohydrate on Post-exercise Muscle Glycogen Synthesis Rate.

The aim of the present study is to investigate the effect of added protein+leucine or caffeine to 1.2 g/kg/h CHO on the rate of post-exercise muscle glycogen re-synthesis in healthy, recreational athletes.

The investigators hypothesize that both interventions (the addition of caffeine or protein+leucine) will lead to higher glycogen re-synthesis compared to the ingestion of CHO only, and that the co-ingestion of protein and leucine will result in the highest muscle glycogen synthesis rates.

Not Provided
Interventional
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Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Double Blind (Subject, Investigator)
Primary Purpose: Basic Science
Exercise Recovery
  • Dietary Supplement: Carbohydrate
    1.2 g/kg/h
  • Dietary Supplement: Carbohydrate and protein ingestion
    1.2 g/kg/h carbohydrate plus 0.4 g/kg/h protein
  • Dietary Supplement: Carbohydrate and caffeine ingestion
    1.2 g/kg/h carbohydrate and 1.67 g/kg/h caffeine
  • Experimental: 1
    Carbohydrate ingestion
    Intervention: Dietary Supplement: Carbohydrate
  • Experimental: 2
    Carbohydrate and protein ingestion
    Intervention: Dietary Supplement: Carbohydrate and protein ingestion
  • Experimental: 3
    Carbohydrate and caffeine ingestion
    Intervention: Dietary Supplement: Carbohydrate and caffeine ingestion
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
14
September 2009
September 2009   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • male cyclists
  • healthy
  • BMI < 25

Exclusion Criteria:

  • female
  • use of medication
  • non cycling
  • BMI > 25
Male
18 Years to 35 Years   (Adult)
Yes
Contact information is only displayed when the study is recruiting subjects
Netherlands
 
NCT00975390
08-3-066
No
Not Provided
Not Provided
Milou Beelen, Maastricht University Medical Center
Maastricht University Medical Center
Not Provided
Not Provided
Maastricht University Medical Center
April 2015

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP