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Exercise, Oxidative Stress and HIV

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00950937
First Posted: August 3, 2009
Last Update Posted: August 11, 2009
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Hospital de Clinicas de Porto Alegre
February 16, 2009
August 3, 2009
February 16, 2009
August 3, 2009
August 11, 2009
June 2006
January 2007   (Final data collection date for primary outcome measure)
Total Glutathione [ Time Frame: 3 times - baseline (before the peak oxygen uptake test), aerobic (immediately after aerobic exercise) and resistance (immediately after resistance exercise). ]
Same as current
Complete list of historical versions of study NCT00950937 on ClinicalTrials.gov Archive Site
  • Catalase Activity [ Time Frame: 3 times - baseline (before the peak oxygen uptake test), aerobic (immediately after aerobic exercise) and resistance (immediately after resistance exercise). ]
  • Glutathione S-transferase (GST) [ Time Frame: 3 times - baseline (before the peak oxygen uptake test), aerobic (immediately after aerobic exercise) and resistance (immediately after resistance exercise). ]
  • Lipid Peroxidation [ Time Frame: 3 times - baseline (before the peak oxygen uptake test), aerobic (immediately after aerobic exercise) and resistance (immediately after resistance exercise). ]
  • T CD4 [ Time Frame: 3 times - baseline (before the peak oxygen uptake test), aerobic (immediately after aerobic exercise) and resistance (immediately after resistance exercise). ]
  • Neutrophil Count [ Time Frame: 3 times - baseline (before the peak oxygen uptake test), aerobic (immediately after aerobic exercise) and resistance (immediately after resistance exercise). ]
  • Peak Oxygen Uptake [ Time Frame: 1 time, before the exercise protocol ]
Same as current
Not Provided
Not Provided
 
Exercise, Oxidative Stress and HIV
A Case-control Study to Test the Effects of a Bout of Aerobic Exercise Followed by Resistance Training on Antioxidant System in Human Immunodeficiency Virus (HIV)-Infected and Non-HIV Subjects
The purpose of this study is to compare oxidative stress markers and the immunologic characteristics of HIV-infected and non-HIV subjects during a bout of moderate aerobic exercise followed by resistance exercises
Not Provided
Observational
Observational Model: Case Control
Time Perspective: Prospective
Not Provided
Not Provided
Non-Probability Sample
The participants of the HIV group were recruited at the outpatient HIV/AIDS care unit of the Hospital de Clínicas de Porto Alegre (HCPA), whereas the control group (non-HIV) was formed by volunteers of the city of Porto Alegre, Rio Grande do Sul, Brazil
HIV Infections
Not Provided
  • HIV Group
    HIV infected persons
  • Control Group
    Non HIV-infected persons
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
28
July 2008
January 2007   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • HIV Group:without contraindications for exercise training; to highly active antiretroviral therapy (HAART) for at least 6 months before enrollment; be classified as low level of physical activity by international physical activity questionnaire (IPAQ) and did not use antioxidant supplements.
  • Control Group:negative result for HIV-1 test and the other criteria described above

Exclusion Criteria:

  • Subjects with previous history of cardiovascular and neurological disease, diabetes, dyslipidemia, tobacco using, physical disability and pregnant women were excluded from the study.
Sexes Eligible for Study: All
20 Years to 55 Years   (Adult)
Yes
Contact information is only displayed when the study is recruiting subjects
Brazil
 
 
NCT00950937
06067
Yes
Not Provided
Not Provided
Pedro Dall'Ago, Hospital de Clinicas de Porto Alegre
Hospital de Clinicas de Porto Alegre
Not Provided
Principal Investigator: Pedro Dall'Ago, Professor Hospital de Clinicas de Porto Alegre
Hospital de Clinicas de Porto Alegre
August 2009