ClinicalTrials.gov
ClinicalTrials.gov Menu

The Early Origins of Cardiovascular Disease

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT00923039
Recruitment Status : Unknown
Verified June 2009 by Danone Institute International.
Recruitment status was:  Not yet recruiting
First Posted : June 18, 2009
Last Update Posted : June 18, 2009
Sponsor:
Information provided by:
Danone Institute International

June 17, 2009
June 18, 2009
June 18, 2009
June 2009
Not Provided
To determine how size at birth and growth during infancy and childhood affect: body composition, cardiac structure and function, vascular and endothelial function, renal function, metabolic status and transcriptional and epigenetic characteristics [ Time Frame: 3 years ]
Same as current
No Changes Posted
Not Provided
Not Provided
Not Provided
Not Provided
 
The Early Origins of Cardiovascular Disease
The Early Origins of Cardiovascular Disease : the Consequence of Growth Restriction During Foetal Life and Infancy on Cardiovascular Structure and Function in Adulthood

Small body size at birth, slow weight gain during infancy and increase in body mass index after 2 years are independent risk factors for cardiovascular disease and the metabolic syndrome. There is a large gap in our understanding of how early growth affects the cardiovascular system. Possible mechanisms include alterations in body composition, in cardiac structure, in vascular function, in renal function and epigenetic processes.

The Objective is to determine how size at birth and growth during infancy and childhood affect: body composition, cardiac structure and function, vascular and endothelial function, renal function, metabolic status and transcriptional and epigenetic characteristics.

Not Provided
Observational
Observational Model: Cohort
Time Perspective: Retrospective
Not Provided
Not Provided
Non-Probability Sample
200 Young adult students will be recruited at the Preventive Medicine Centre at Université de la Méditerranée during their annual routine medical examination
Cardiovascular Disease
Not Provided
Exposed/ Not exposed
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Unknown status
200
Same as current
Not Provided
Not Provided

Inclusion Criteria:

  • Male and female volunteers students aged between 18-25 years old
  • Having growth records

Exclusion Criteria:

  • If young women subject without contraception,or pregnant
Sexes Eligible for Study: All
18 Years to 25 Years   (Adult)
Yes
Contact information is only displayed when the study is recruiting subjects
France
 
 
NCT00923039
NU 304
Not Provided
Not Provided
Not Provided
Dardaine /General representative, Danone Institute International
Danone Institute International
Not Provided
Not Provided
Danone Institute International
June 2009