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Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors

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ClinicalTrials.gov Identifier: NCT00919750
Recruitment Status : Completed
First Posted : June 12, 2009
Last Update Posted : July 16, 2018
Sponsor:
Collaborator:
National Cancer Institute (NCI)
Information provided by (Responsible Party):
Children's Oncology Group

June 11, 2009
June 12, 2009
July 16, 2018
February 16, 2004
June 30, 2018   (Final data collection date for primary outcome measure)
  • Collection of brain tumor tissue and an accompanying blood sample from pediatric patients with brain tumors treated at Children?s Oncology Group institutions [ Time Frame: Up to 16 years ]
  • Creation of a repository for long-term storage of these specimens [ Time Frame: Up to 16 years ]
  • Making these specimens available to qualified researchers to understand the biology of pediatric brain tumors [ Time Frame: Up to 16 years ]
  • Collection of brain tumor tissue and an accompanying blood sample from pediatric patients with brain tumors treated at Children's Oncology Group institutions
  • Creation of a repository for long-term storage of these specimens
  • Making these specimens available to qualified researchers to understand the biology of pediatric brain tumors
Complete list of historical versions of study NCT00919750 on ClinicalTrials.gov Archive Site
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Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors
A Children's Oncology Group Protocol for Collecting and Banking Pediatric Brain Tumor Research Specimens
The purpose of this study is to collect and store brain tissue samples and blood from children with brain cancer that will be tested in the laboratory. Collecting and storing samples of tumor tissue and blood from patients to test in the laboratory may help the study of cancer in the future.

OBJECTIVES:

I. Collect brain tumor tissue and an accompanying blood sample from pediatric patients with brain tumors treated at Children?s Oncology Group institutions.

II. Provide a repository for long-term storage of specimens from these patients.

III. Make these specimens available to qualified researchers to understand the biology of pediatric brain tumors.

OUTLINE: This is a multicenter study.

Brain tumor tissue and blood specimens are collected from patients and banked for future study.

Observational
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Non-Probability Sample
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  • Childhood Atypical Teratoid/Rhabdoid Tumor
  • Childhood Central Nervous System Germ Cell Tumor
  • Childhood Cerebral Anaplastic Astrocytoma
  • Childhood Cerebral Astrocytoma
  • Childhood Choroid Plexus Neoplasm
  • Childhood Craniopharyngioma
  • Childhood Grade I Meningioma
  • Childhood Grade II Meningioma
  • Childhood Grade III Meningioma
  • Childhood Infratentorial Ependymoma
  • Childhood Oligodendroglioma
  • Childhood Supratentorial Ependymoma
  • Ependymoma
  • Newly Diagnosed Childhood Ependymoma
  • Recurrent Childhood Cerebellar Astrocytoma
  • Recurrent Childhood Cerebral Astrocytoma
  • Recurrent Childhood Ependymoma
  • Recurrent Childhood Medulloblastoma
  • Recurrent Childhood Supratentorial Embryonal Tumor, Not Otherwise Specified
  • Recurrent Childhood Visual Pathway Glioma
Other: Cytology Specimen Collection Procedure
Correlative studies
Other Name: Cytologic Sampling
Ancillary-Correlative (tissue and blood sample collection)
Brain tumor tissue and blood specimens are collected from patients and banked for future study.
Intervention: Other: Cytology Specimen Collection Procedure
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
1258
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June 30, 2018
June 30, 2018   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • Diagnosis of brain tumor
  • Previously treated at a Children?s Oncology Group (COG) institution

    • Patients are eligible at time of diagnosis, second-look surgery, recurrence, or development of a second malignant neoplasm
  • Must have brain tumor biological specimens derived from primary tumors of the CNS available for submission
Sexes Eligible for Study: All
up to 18 Years   (Child, Adult)
No
Contact information is only displayed when the study is recruiting subjects
Australia,   Canada,   New Zealand,   Puerto Rico,   Switzerland,   United States
 
 
NCT00919750
ACNS02B3
NCI-2009-00334 ( Registry Identifier: CTRP (Clinical Trial Reporting Program) )
COG-ACNS02B3
CDR0000352347
ACNS02B3 ( Other Identifier: Childrens Oncology Group )
ACNS02B3 ( Other Identifier: CTEP )
U10CA098543 ( U.S. NIH Grant/Contract )
UG1CA189958 ( U.S. NIH Grant/Contract )
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Children's Oncology Group
Children's Oncology Group
National Cancer Institute (NCI)
Principal Investigator: Scott Pomeroy Children's Oncology Group
Children's Oncology Group
July 2018