Now Available: Final Rule for FDAAA 801 and NIH Policy on Clinical Trial Reporting

Discard:Characterisation of Colonic Polyps in Vivo (DISCARD)

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Imperial College London
ClinicalTrials.gov Identifier:
NCT00888771
First received: April 27, 2009
Last updated: February 11, 2016
Last verified: July 2010

April 27, 2009
February 11, 2016
August 2008
February 2009   (final data collection date for primary outcome measure)
Accuracy of polyp characterisation [ Time Frame: 12 months ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT00888771 on ClinicalTrials.gov Archive Site
Change in surveillance interval after formal histopathology [ Time Frame: 12 months ] [ Designated as safety issue: No ]
Same as current
Not Provided
Not Provided
 
Discard:Characterisation of Colonic Polyps in Vivo
Characterisation of Small Colonic Polyps in Vivo
Prospective study of accuracy of colonic polyp characterisation in vivo using high resolution white light endoscopy, narrow band imaging and chromoendoscopy.
Not Provided
Observational
Observational Model: Cohort
Time Perspective: Prospective
Not Provided
Not Provided
Non-Probability Sample
The study group therefore would comprise those presenting for 3 yearly follow up or sooner i.e. those with a resected colorectal cancer or those with ≥ three adenomas or one advanced ≥10mm adenoma or those with a positive faecal occult blood test
Colorectal Polyps
Not Provided
  • 1
  • 2
  • 3
  • 4
Ignjatovic A, East JE, Suzuki N, Vance M, Guenther T, Saunders BP. Optical diagnosis of small colorectal polyps at routine colonoscopy (Detect InSpect ChAracterise Resect and Discard; DISCARD trial): a prospective cohort study. Lancet Oncol. 2009 Dec;10(12):1171-8. doi: 10.1016/S1470-2045(09)70329-8.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
130
June 2009
February 2009   (final data collection date for primary outcome measure)

Inclusion Criteria:

  1. Patients over 18 years of age, assessed as fit for routine colonoscopy
  2. Patients attending for screening or surveillance colonoscopy meeting the following criteria:

    • Polyp surveillance with at least 3 adenomas or 1 adenoma>10mm at previous colonoscopy
    • Surveillance post colorectal cancer resection
    • Screening with positive faecal occult blood test

Exclusion Criteria:

  1. Patients with known colitis or polyposis syndromes
  2. Unable or unwilling to give informed consent
Both
18 Years and older   (Adult, Senior)
Yes
Contact information is only displayed when the study is recruiting subjects
United Kingdom
 
NCT00888771
05/Q0405/121/1
No
Not Provided
Not Provided
Imperial College London
Imperial College London
Not Provided
Principal Investigator: Brian P Saunders, MD Wolfson Unit for Endoscopy, St Mark's Hospital
Imperial College London
July 2010

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP