Exercise Following Autologous Peripheral Blood Stem Cell Transplantation

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00883961
Recruitment Status : Unknown
Verified December 2009 by Charite University, Berlin, Germany.
Recruitment status was:  Recruiting
First Posted : April 20, 2009
Last Update Posted : December 23, 2009
Information provided by:
Charite University, Berlin, Germany

April 17, 2009
April 20, 2009
December 23, 2009
December 2009
April 2011   (Final data collection date for primary outcome measure)
VO2max [ Time Frame: At recruitment and after 3 weeks ]
Same as current
Complete list of historical versions of study NCT00883961 on Archive Site
  • Mood [ Time Frame: At recruitment and after 3 weeks ]
  • Duration of aplasia [ Time Frame: 3 weeks ]
  • Complications during hospitalization [ Time Frame: 3 weeks ]
  • Need for transfusion of platelets and red blood cells [ Time Frame: 3 weeks ]
Same as current
Not Provided
Not Provided
Exercise Following Autologous Peripheral Blood Stem Cell Transplantation
Not Provided
The study evaluates the effects of a supervised exercise program on the physical performance, the mood and the complications of therapy in patients undergoing a high-dose chemotherapy followed by an autologous peripheral blood stem cell transplantation.
Not Provided
Phase 3
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Investigator)
Primary Purpose: Supportive Care
Hematological Disease
Other: Supervised exercise
The patients will carry out a daily endurance exercise program consisting of walking on a treadmill for 30 minutes at an intensity of about 80% of the maximum heart rate under supervision from study personnel.
  • Experimental: Supervised exercise
    Intervention: Other: Supervised exercise
  • No Intervention: Control group
    The patients will not carry out a structured exercise program.
Not Provided

*   Includes publications given by the data provider as well as publications identified by Identifier (NCT Number) in Medline.
Unknown status
Same as current
September 2011
April 2011   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • Age 18-70
  • Hematological disease
  • Treatment with high-dose chemotherapy followed by autologous stem cell transplantation
  • Understanding of written German

Exclusion Criteria:

  • Cardiorespiratory, metabolical, osteoarticular or immunological diseases which can be aggravated by exercise
  • Pathological stress-ECG at admission
Sexes Eligible for Study: All
18 Years to 70 Years   (Adult, Older Adult)
Contact information is only displayed when the study is recruiting subjects
Not Provided
Not Provided
Dr. Fernando Dimeo, Dept. of Sports Medicine, Charité Universitätsmedizin Berlin
Charite University, Berlin, Germany
Not Provided
Principal Investigator: Fernando Dimeo, MD Charite University, Berlin, Germany
Charite University, Berlin, Germany
December 2009

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP