ClinicalTrials.gov
ClinicalTrials.gov Menu

Whole-Body MRA at 3T - A Comparison Between Two Different Scan Protocols

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT00834548
Recruitment Status : Completed
First Posted : February 3, 2009
Last Update Posted : February 3, 2009
Sponsor:
Collaborator:
Rigshospitalet, Denmark
Information provided by:
Copenhagen University Hospital at Herlev

August 26, 2008
February 3, 2009
February 3, 2009
June 2008
Not Provided
Diagnostic quality of WB-MRA
Same as current
No Changes Posted
  • Signal to noise ratio
  • Contrast to noise ratio
Same as current
Not Provided
Not Provided
 
Whole-Body MRA at 3T - A Comparison Between Two Different Scan Protocols
Whole-Body MRA at 3T - A Comparison Between Two Different Scan Protocols

To compare to different approaches in whole-body magnetic resonance angiography of patients suffering peripheral arterial disease.

Our hypothesis is that use of a new protocol improves the diagnostic quality of the WB-MRA procedure.

Patients suffering peripheral arterial disease must undergo imaging procedures before endovascular or surgical procedures.

WB-MRA is an imaging procedure that can visualise the arterial system. WB-MRA can be performed in different manners. On option is to start the scan in the head region and continue down the body to the feet (standard protocol). Another option is to use a hybrid protocol that first examines the head and lower leg followed by examination of the pelvic and upper leg region.

A comparison between the standard and hybrid protocols has not been performed in a 3T high magnetic field system, therefore we will perform such a study.

Observational
Observational Model: Cohort
Time Perspective: Prospective
Not Provided
Not Provided
Not Provided
Patients with peripheral arterial disease
  • Atherosclerosis
  • Intermittent Claudication
Procedure: Whole body magnetic resonance angiography (WB-MRA)
WB-MRA will be performed once in each patient.
  • 1
    WB-MRA standard protocol
    Intervention: Procedure: Whole body magnetic resonance angiography (WB-MRA)
  • 2
    WB-MRA hybrid protocol
    Intervention: Procedure: Whole body magnetic resonance angiography (WB-MRA)
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
26
Same as current
August 2008
Not Provided

Inclusion Criteria:

  • Symptomatic lower extremity ischemia (claudication, ischemic wounds)
  • Referred to digital subtraction angiography (DSA)

Exclusion Criteria:

  • Renal insufficiency (GFR < 30 ml/min)
  • Contra-indications for MRI-examination (claustrophobia, metal-implants, pacemaker)
  • Dementia
  • Pregnancy/lactation
  • Allergy to gadolinium based MRI contrast agents
  • Acute disease
Sexes Eligible for Study: All
18 Years and older   (Adult, Older Adult)
No
Contact information is only displayed when the study is recruiting subjects
Denmark
 
 
NCT00834548
Herlev WB-MRA 5
Yes
Not Provided
Not Provided
Yousef Nielsen MD, Copenhagen University Hospital Herlev
Copenhagen University Hospital at Herlev
Rigshospitalet, Denmark
Principal Investigator: Yousef W Nielsen, MD Copenhagen University Hospital at Herlev
Copenhagen University Hospital at Herlev
February 2009