Observational Trial of Hepatitis C Virus Infected Patients on Calcineurin Inhibitors

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
University of Wisconsin, Madison
ClinicalTrials.gov Identifier:
NCT00819026
First received: January 6, 2009
Last updated: December 9, 2014
Last verified: December 2014

January 6, 2009
December 9, 2014
October 2008
August 2013   (final data collection date for primary outcome measure)
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Not Provided
Complete list of historical versions of study NCT00819026 on ClinicalTrials.gov Archive Site
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Observational Trial of Hepatitis C Virus Infected Patients on Calcineurin Inhibitors
Not Provided

Hepatitis C Virus is constantly evolving genetically, particularly in response to the immune system. This is an observational study to examine if immunosuppressants particularly calcineurin inhibitors taken by transplant patients in order to avoid organ rejection causes predictable changes in the genetics of this virus that might be important in order to treat it effectively.

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Observational
Time Perspective: Cross-Sectional
Not Provided
Retention:   Samples Without DNA
Description:

viral RNA

Non-Probability Sample

solid organ transplant patients

Hepatitis C Virus
Not Provided
Not Provided
Ansari IU, Allen T, Berical A, Stock PG, Barin B, Striker R. Phenotypic analysis of NS5A variant from liver transplant patient with increased cyclosporine susceptibility. Virology. 2013 Feb 20;436(2):268-73. doi: 10.1016/j.virol.2012.11.018. Epub 2013 Jan 2.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
15
August 2013
August 2013   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • HCV infected on immunosuppression
Both
18 Years to 70 Years
No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00819026
UWisHCV-1
No
University of Wisconsin, Madison
University of Wisconsin, Madison
Not Provided
Principal Investigator: Robert Striker University of Wisconsin, Madison
University of Wisconsin, Madison
December 2014

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP