Examination of B Cell Responses in Human Blood

This study has been completed.
Sponsor:
Collaborator:
University of Leipzig
Information provided by (Responsible Party):
Christian Jassoy, Regenerative Medicine Network
ClinicalTrials.gov Identifier:
NCT00806845
First received: December 10, 2008
Last updated: May 12, 2015
Last verified: May 2015

December 10, 2008
May 12, 2015
July 2008
December 2009   (final data collection date for primary outcome measure)
Antigen specific B-cell responses [ Time Frame: 18 months ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT00806845 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
Examination of B Cell Responses in Human Blood
Gewinnung Humaner antikörperproduzierender Zellen Aus Dem Blut

The aim of this study is the assessment B-cell immune responses in HIV-infected individuals.

Groups of patients with different immune competencies will be examined. The impact of HIV infection on immune response will be assessed.

Observational
Observational Model: Cohort
Time Perspective: Cross-Sectional
Not Provided
Retention:   Samples Without DNA
Description:

peripheral blood

Non-Probability Sample

HIV patients and controls attending specialised clinics, Germany

HIV Infections
Not Provided
  • HIV infected individuals, HIV controllers
    CD4+ T cell count > 350/µl, HIV load < 1000 copies/ml
  • HIV infected individuals, early progressors
    CD4+ T cell count > 350/µl, HIV load > 1000 copies/ml
  • HIV infected individuals, late progressors
    CD4+ T cell count < 200/µl
  • HIV infected individuals, late progressors with therapy
    CD4+ T cell count < 200/µl, under ART
  • Healthy individuals
    Uninfected

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
50
February 2010
December 2009   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • HIV-infected individuals
  • controls

Exclusion Criteria:

- none

Both
18 Years to 65 Years
Yes
Contact information is only displayed when the study is recruiting subjects
Germany
 
NCT00806845
RegMedNet-001
Yes
Christian Jassoy, Regenerative Medicine Network
Regenerative Medicine Network
University of Leipzig
Study Director: Christian Jassoy, MD Universität Leipzig
Regenerative Medicine Network
May 2015

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP