Adventure: Teacher Delivered Personality-targeted Interventions for Substance Misuse (Adventure)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00776685
Recruitment Status : Completed
First Posted : October 21, 2008
Last Update Posted : June 27, 2011
Action on Addiction
Information provided by:
King's College London

October 17, 2008
October 21, 2008
June 27, 2011
May 2007
March 2010   (Final data collection date for primary outcome measure)
  • Binge drinking frequency [ Time Frame: 2 years ]
    Frequency in the past 6 months that subject reported drinking 5 or more alcoholic beverages (4 or more for girls) on one drinking occasion.
  • Drinking frequency [ Time Frame: 2 years ]
    Past six months frequency of drinking
  • drinking quantity [ Time Frame: 2 years ]
    Average number of alcoholic beverages consumed on a typical drinking occasion in the past six months
  • Drinking problems [ Time Frame: 2 years ]
    number of drinking problems reported on an abbreviated version of the Rutger's Alcohol Problem Index.
  • illicit drug use events [ Time Frame: 2 years ]
    Time to onset of illicit drug use
Time to onset and severity of alcohol and drug use and misuse [ Time Frame: 2 years ]
Complete list of historical versions of study NCT00776685 on Archive Site
Emotional and behavioural problems, targeted and school-wide effects [ Time Frame: 2 years ]
Psychiatric symptoms (depression, panic anxiety, antisocial behaviours), coping skills, motives for drinking, school attendance and attainment, in-class behaviours assessed using the Strengths and Difficulties Questionnaire and the Brief Symptom Inventory.
Psychiatric symptoms (depression, panic anxiety, antisocial behaviours), coping skills, motives for drinking [ Time Frame: 2 years ]
Not Provided
Not Provided
Adventure: Teacher Delivered Personality-targeted Interventions for Substance Misuse
Cognitive Behavioral Interventions That Target Personality Risk for Substance Abuse and Mental Illness: Delivery by Educational Professionals
Several personality factors have been shown to be associated with risk for alcohol and substance misuse, and differentiate substance abusers based on clinical profile, treatment response and susceptibility to other forms of mental illness. Personality-targeted interventions have been found to have significant preventative effects on onset and growth of drinking, binge-drinking and drinking problems in adolescents attending mainstream schools (Conrod, Castellanos & Mackie, 2008). The interventions concurrently reduced personality-specific emotional and behavioural problems (Castellanos & Conrod, 2006), and prevented the onset and escalation of drug-use over a two-year period (Conrod, Castellanos-Ryan & Strang, 2010). This cluster randomised controlled trial aims to examine whether these results can be replicated when interventions are delivered by trained educational professionals. In addition, the trial will evaluate the broader impact of the programme on cigarette smoking, school attendance, academic achievement and school-wide behaviours.

The Adventure study aims to examine whether educational professionals such as teachers, mentors or individuals in a pastoral role, who are trained in carrying out personality-targeted interventions will be effective in reducing problem behaviours in a group of adolescents.

20 schools in London, U.K. were recruited for the trial, and over 2000 adolescents (mean age 13.7 years) consented to participate in the survey and intervention phases of the trial. Schools were randomly assigned to control or intervention condition, and students in intervention schools who met the criteria for any of the 4 personality risk subscales of the Substance Use Risk Profile Scale (Negative Thinking, Anxiety Sensitivity, Sensation Seeking and Impulsivity) were invited to participate in a personality-targeted intervention by trained members of staff from their schools. All participants were invited to complete follow-up surveys at 6-month intervals for 2 years. The remaining 55% of low risk students in the grad were also followed to examine population-level effects of the intervention as well.

The main outcome measures of this RCT are alcohol and illicit drug outcomes. Secondary measures include mental health symptoms, risky behaviour, school attainment and attendance, and school-wide behaviours.

It is hypothesised that teacher-delivered personality-targeted interventions will have similar preventative effects on alcohol and drug use as reported by Conrod et al (2008, 2010), in addition to the personality-specific intervention effects reported by Castellanos & Conrod (2006). In addition, broader effects of the intervention on academic achievement and school-wide behaviour will be examined in this trial, both at the individual level and at the population-level.

Phase 2
Phase 3
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
  • Alcohol Abuse
  • Drug Abuse
  • Depression
  • Panic Disorder
  • Conduct Disorder
Behavioral: Personality-targeted interventions
Motivational and cognitive behavioural interventions targeting four personality profiles. 2 90 minute group sessions with personality-matched peers facilitated by a trained teacher and co-facilitator
Other Name: Preventure, but now delivered by teachers
  • Experimental: learning to cope with your impulsivity
    Cognitive-behavioural intervention targeting impulsive personality
    Intervention: Behavioral: Personality-targeted interventions
  • Experimental: learning to cope with your sensation seeking
    cognitive behavioural intervention designed to help sensation seeking youth manage their need for stimulation and excitement.
    Intervention: Behavioral: Personality-targeted interventions
  • Experimental: learning to cope with your anxiety sensitivity
    cognitive behavioural intervention teaching anxiety sensitive youth to manager their sensitivity to threat and anxiety.
    Intervention: Behavioral: Personality-targeted interventions
  • Experimental: learning to manage your negative thinking
    cognitive behavioural intervention targeting pessimistic and negative thinking in hopeless youth
    Intervention: Behavioral: Personality-targeted interventions

*   Includes publications given by the data provider as well as publications identified by Identifier (NCT Number) in Medline.
Same as current
May 2010
March 2010   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • Secondary school student

Exclusion Criteria:

Sexes Eligible for Study: All
13 Years to 16 Years   (Child)
Contact information is only displayed when the study is recruiting subjects
United Kingdom
Not Provided
Not Provided
Dr. Patricia Conrod, Institute of Psychiatry, King's College London
King's College London
Action on Addiction
Study Chair: Patricia J Conrod, PhD King's College London
King's College London
December 2010

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP