We updated the design of this site on September 25th. Learn more.
Show more
ClinicalTrials.gov
ClinicalTrials.gov Menu

Surveillance of Influenza Virus Among Children With Febrile Respiratory Complaints Attending the Pediatric Clinic of the First Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong, Mainland China

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00760500
First Posted: September 26, 2008
Last Update Posted: February 18, 2015
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborators:
The University of Hong Kong
National Institute of Allergy and Infectious Diseases (NIAID)
Information provided by (Responsible Party):
St. Jude Children's Research Hospital
September 25, 2008
September 26, 2008
February 18, 2015
January 2004
March 2014   (Final data collection date for primary outcome measure)
To identify Influenza A or B and the subtype of Influenza A of the isolates from children with febrile respiratory complaints who attend the pediatric clinic of the First Affiliated Hospital, Shantou University Medical College. [ Time Frame: This is an epidemiologic study, there is no time frame. ]
Same as current
Complete list of historical versions of study NCT00760500 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
Surveillance of Influenza Virus Among Children With Febrile Respiratory Complaints Attending the Pediatric Clinic of the First Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong, Mainland China
Surveillance of Influenza Virus Among Children With Febrile Respiratory Complaints Attending the Pediatric Clinic of the First Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong, Mainland China
The surveillance of influenza virus among children with febrile reparatory complaints attending the pediatric clinic in Shantou is an epidemiologic study to identify the type (influenza A or B) and the subtype of Influenza A of the isolates from children with febrile respiratory complaints who attend the pediatric clinic of the first Affiliated Hospital, Shantou University Medical College, Shantou Guangdong, China. Also this study investigates the genetic composition of all segments of isolated strains using standard molecular techniques and to make available the new strains of influenza viruses isolated from such children for the formulation of influenza vaccines. Clinical manifestation of the respiratory illness is recorded and single nasopharyngeal swab is obtained from eligible children. Viral culture is performed on the nasopharyngeal secretions. If influenza is isolated, this is characterized if it belongs to influenza A or B. If the virus is characterized as influenza A, further antigenic studies is done to determine subtype of influenza. Viral isolates is further studied to determine the genetic composition of the virus. Information obtained from the viral isolates is shared with the WHO and the CDC.

OBJECTIVES

Primary objective:

  • To identify the type (Influenza A or B) and the subtype of Influenza A of the isolates from children with febrile respiratory complaints who attend the pediatric clinic of the First Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong, China.

Secondary objectives

  • To investigate the genetic composition of all segments of isolated strains using standard molecular techniques.
  • To make available the new strains of influenza viruses isolated from such children for the formulation of influenza vaccines.
Observational
Observational Model: Ecologic or Community
Time Perspective: Prospective
Not Provided
Retention:   Samples Without DNA
Description:
Nasopharyngeal specimen taken by swab
Non-Probability Sample
Children between the ages of 0 months and 18 years (inclusive) who have been seen at the pediatric clinic of the First Affiliated Hospital within 7 days of the onset of signs and symptoms of febrile respiratory illness suspected to be of viral origin (temperature > 37.7ºC or reliable history of fever before being examined, and respiratory symptoms and signs such as cough, sore throat, and coryza).
  • Influenza Type A
  • Influenza Type B
Other: Nasopharyngeal Swab
Nasopharyngeal Swab
1
Intervention: Other: Nasopharyngeal Swab
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
13201
March 2014
March 2014   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • Age: 0 day to 18 years.
  • Patient was seen at the pediatric clinic of the First Affiliated Hospital within 7 days of the onset of signs and symptoms of febrile respiratory illness suspected to be of viral origin (temperature > 37.7ºC or reliable history of fever before being examined, and respiratory symptoms and signs such as cough, sore throat, and coryza).
  • Parents agree to a nasopharyngeal specimen being taken by swab from their child.

Exclusion Criteria:

  • Patient is too ill to tolerate a nasopharyngeal specimen swab.
Sexes Eligible for Study: All
up to 18 Years   (Child, Adult)
No
Contact information is only displayed when the study is recruiting subjects
China
 
 
NCT00760500
SIVFRC
N01AI70005 ( Other Grant/Funding Number: NIAID )
No
Not Provided
Not Provided
St. Jude Children's Research Hospital
St. Jude Children's Research Hospital
  • The University of Hong Kong
  • National Institute of Allergy and Infectious Diseases (NIAID)
Principal Investigator: Miguela Caniza, MD St. Jude Children's Research Hospital
St. Jude Children's Research Hospital
February 2015