We updated the design of this site on September 25th. Learn more.
Show more
ClinicalTrials.gov
ClinicalTrials.gov Menu

Oxidative Stress in Critical Ill Patients in Surgical Intensive Care Unit

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified August 2009 by National Taiwan University Hospital.
Recruitment status was:  Recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT00745888
First Posted: September 3, 2008
Last Update Posted: September 9, 2009
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
National Taiwan University Hospital
September 2, 2008
September 3, 2008
September 9, 2009
May 2007
Not Provided
28-day Survival [ Time Frame: 28 days ]
Same as current
Complete list of historical versions of study NCT00745888 on ClinicalTrials.gov Archive Site
Days stay in ICU Days on ventilator SOFA score Complications [ Time Frame: 28 days ]
Same as current
Not Provided
Not Provided
 
Oxidative Stress in Critical Ill Patients in Surgical Intensive Care Unit
Oxidative Stress in Critical Ill Patients in Surgical Intensive Care Unit

In clinical practice, the oxidative stress is related to circulatory shock, sepsis, acute lung injury, and acute respiratory distress syndrome. There are some questions on the oxidative stress of the critical illness. First, the investigators want to search out the effects of the past history, smoking, alcohol drinking, use of antioxidants, different diseases, and different duration of SIRS on the degree of oxidative stress. Second, besides total count of ROS, the investigators used new techniques to determine superoxide(O2●-), hydrogen peroxide (H2O2), and hypochlorous acid(HOCl). Furthermore, we want to investigate the correlation of the degree of different reactive oxygen species and the severity of SIRS or shock. Third, we try to investigate the correlation between the change of oxidative stress and the prognosis of the patients.

The investigators wish this study will help them to investigate the effect of oxidative stress on critical ill patients, to modulate the oxidative stress, to decrease the occurrence of SIRS, shock, and multiorgan failure, and to improve the long term outcome of patients.

Not Provided
Observational
Time Perspective: Prospective
Not Provided
Retention:   Samples Without DNA
Description:
blood sample
Probability Sample
Patients admitted to surgical ICU
  • Sepsis
  • Shock
Other: Chemiluminescence Analyzer
measure reactive oxygen species
1
age > 18 y/o Patients admitted to surgical ICU
Intervention: Other: Chemiluminescence Analyzer
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Unknown status
200
Not Provided
Not Provided

Inclusion Criteria:

  • Age > 18 y/o
  • Admitted to surgical ICU

Exclusion Criteria:

  • Patients with brain death
Sexes Eligible for Study: All
18 Years and older   (Adult, Senior)
No
Contact information is only displayed when the study is recruiting subjects
Taiwan
 
 
NCT00745888
9561709132
No
Not Provided
Not Provided
Yu-Chang Yeh, National Taiwan University Hospital
National Taiwan University Hospital
Not Provided
Principal Investigator: Yu-Chang Yeh National Taiwan University Hospital
National Taiwan University Hospital
August 2009