Cognitive and Functional Status and Dialysis Outcomes in Older Hemodialysis Patients

This study has been terminated.
Sponsor:
Information provided by (Responsible Party):
University of Chicago
ClinicalTrials.gov Identifier:
NCT00739843
First received: August 20, 2008
Last updated: October 31, 2016
Last verified: October 2016

August 20, 2008
October 31, 2016
November 2007
September 2010   (Final data collection date for primary outcome measure)
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Complete list of historical versions of study NCT00739843 on ClinicalTrials.gov Archive Site
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Cognitive and Functional Status and Dialysis Outcomes in Older Hemodialysis Patients
Cognitive and Functional Status and Dialysis Outcomes in Older Hemodialysis Patients
The purpose of this study is to estimate how quickly cognitive status and functional status in older patients on hemodialysis declines.
Dialysis outcome measures, which predict morbidity and mortality of younger patients on renal replacement therapy, such as dialysis clearance, do not correlate with survival of the elderly patients on hemodialysis. Survival of older patients on hemodialysis is significantly worse when compared to that of the younger patients. Conditions commonly affecting older adults, such as functional decline, cognitive impairment, depression and declining quality of life have not been well studied in hemodialysis population. There may be an important relationship between these measurements and outcomes in older dialysis patients. Institution of appropriate age-specific interventions could result in improved health status and mortality of older patients on hemodialysis. Our broad objective is to better understand global functioning of the elderly dialysis patients and its possible impact on dialysis outcomes in attempt to improve health care of the older patients receiving hemodialysis.
Observational
Observational Model: Cohort
Time Perspective: Prospective
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Non-Probability Sample
All prevalent and incident hemodialysis patients over the age of 60, receiving hemodialysis treatments at the University of Chicago outpatient dialysis program at the time of the study will be invited to participate.
  • Dementia
  • Cognition
  • End-stage Renal Disease
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Terminated
55
September 2010
September 2010   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • Prevalent and incident hemodialysis patients over the age of 60, receiving hemodialysis treatments at the University of Chicago outpatient dialysis program.

Exclusion Criteria:

  • Patients 59 and younger, and patients with the following medical conditions: malignancies currently requiring chemotherapy or radiation therapy, severe heart failure (NYHA class IV), known HIV infection, or currently active hepatic encephalopathy.
Sexes Eligible for Study: All
60 Years and older   (Adult, Senior)
No
Contact information is only displayed when the study is recruiting subjects
United States
 
 
NCT00739843
15813B
Yes
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University of Chicago
University of Chicago
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Principal Investigator: Nicole Stankus, MD, MSc University of Chicago
University of Chicago
October 2016

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP