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Efficacy of Transference-Focused Psychotherapy for Borderline Personality Disorder

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00714311
First Posted: July 14, 2008
Last Update Posted: February 16, 2015
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
doerings, University Hospital Muenster
July 9, 2008
July 14, 2008
February 4, 2015
February 16, 2015
February 16, 2015
October 2004
February 2009   (Final data collection date for primary outcome measure)
  • Drop-out [ Time Frame: 1 year ]
    Did not finish one year of treatment.
  • Suicidality (Suicide Attempts) [ Time Frame: 1 year ]
Remission of borderline personality disorder according to the criteria of DSM-IV. [ Time Frame: 1 year ]
Complete list of historical versions of study NCT00714311 on ClinicalTrials.gov Archive Site
  • Psychosocial Functioning (Global Assessment of Functioning, GAF-Score) [ Time Frame: 1 year ]
  • Level of Personality Organization (Structured Interview for Personality Organization, STIPO) [ Time Frame: 1 year ]
  • Number of Self-harming Acts [ Time Frame: 1 year ]
  • Self-assessment of Psychopathology (BDI, STAI, BSI) [ Time Frame: 1 year ]
  • Attachment Style and Reflective Function (Adult Attachment Interview, AAI) [ Time Frame: 1 year ]
  • Borderline Symptomatology (DSM-IV Criteria) [ Time Frame: 1 month ]
  • Psychosocial Functioning (Global Assessment of Functioning, GAF-Score) [ Time Frame: 1 year ]
  • Level of Personality Organization (Structured Interview for Personality Organization, STIPO) [ Time Frame: 1 year ]
  • Number of suicide attempts [ Time Frame: 1 year ]
  • Number of Self-harming Acts [ Time Frame: 1 year ]
  • Self-assessment of Psychopathology (BDI, STAI, BSI) [ Time Frame: 1 year ]
  • Attachment Style and Reflective Function (Adult Attachment Interview, AAI) [ Time Frame: 1 year ]
Not Provided
Not Provided
 
Efficacy of Transference-Focused Psychotherapy for Borderline Personality Disorder
A Randomized-Controlled Trial of Transference-Focused Psychotherapy vs. Treatment by Experienced Community Psychotherapists for Borderline Personality Disorder
The purpose of this study is to find out whether Transference-Focused Psychotherapy (TFP) is effective in the treatment of Borderline Personality Disorder.

Borderline personality disorder represents a sever clinical condition that affects 1-2% of the community and is characterized by a pervasive instability of interpersonal relationships, self-image, and affects, as well as a marked impulsivity; up to 10% of the patients commit suicide.

Transference-Focused Psychotherapy (TFP) is one psychotherapeutic approach among five that have been manualized and evaluated in RCTs. So far, TFP has not been compared to a control condition which is a crucial step in the evaluation of the efficacy of a psychosocial intervention.

This study is an RCT that compares one year of outpatient TFP to treatment by experienced community psychotherapists for borderline personality disorder.

Interventional
Not Provided
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Outcomes Assessor)
Primary Purpose: Treatment
Borderline Personality Disorder
  • Behavioral: Transference-Focused Psychotherapy
    Outpatient psychotherapy according to the treatment manual, sessions of 50 minutes twice per week
  • Behavioral: treatment by experienced community psychotherapists
    Outpatient psychotherapy in private practices or outpatient units of psychiatric hospitals. Licensed psychotherapists with experience and special interest in the treatment of borderline patients are treating according to the method they have learned.
  • Active Comparator: TFP
    Transference-Focused Psychotherapy
    Intervention: Behavioral: Transference-Focused Psychotherapy
  • Active Comparator: ECP
    treatment by experienced community psychotherapists
    Intervention: Behavioral: treatment by experienced community psychotherapists

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
104
February 2015
February 2009   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • Written informed consent to the participation in the study
  • Diagnosis of BPD according to DSM-IV as assessed using the SCID-II
  • Age between 18 and 45 years
  • Sufficient knowledge of the German language

Exclusion Criteria:

  • Diagnosis of schizophrenia, bipolar disorder, severe substance abuse, organic pathology, or mental retardation according to DSM-IV as assessed using the SCID-I
  • Diagnosis of antisocial personality disorder according to DSM-IV as assessed using the SCID-II
Sexes Eligible for Study: Female
18 Years to 45 Years   (Adult)
No
Contact information is only displayed when the study is recruiting subjects
Austria,   Germany
 
 
NCT00714311
1106/04
10636
DPG0802
No
Not Provided
Not Provided
doerings, University Hospital Muenster
University Hospital Muenster
Not Provided
Principal Investigator: Stephan Doering, MD University of Muenster, Germany
University Hospital Muenster
February 2015

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP