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Speech and Language Therapy After Stroke

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ClinicalTrials.gov Identifier: NCT00713050
Recruitment Status : Terminated (Protocol expired; PI retired)
First Posted : July 11, 2008
Last Update Posted : June 11, 2013
Sponsor:
Collaborators:
National Institute on Deafness and Other Communication Disorders (NIDCD)
Shirley Ryan AbilityLab
Information provided by (Responsible Party):
University of Chicago

July 9, 2008
July 11, 2008
June 11, 2013
August 2007
January 2012   (Final data collection date for primary outcome measure)
Changes in scores on Western Aphasia Battery [ Time Frame: Four months ]
Same as current
Complete list of historical versions of study NCT00713050 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
Speech and Language Therapy After Stroke
Neurophysiological Measurement in Aphasia Treatment
Our overall goal is to advance the state of functional brain imaging in aphasia, and then to apply the method to an intensive, imitation-based treatment for non-fluent aphasia.
Detailed information will follow in the next progress report.
Interventional
Not Applicable
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Double (Participant, Outcomes Assessor)
Primary Purpose: Treatment
Ischemic Stroke
Behavioral: Imitate Therapy
Imitation-based computer therapy
Other Name: Imitate
  • Experimental: Experimental
    Computer-based Aphasia therapy
    Intervention: Behavioral: Imitate Therapy
  • Active Comparator: Control
    Control Arm - Healthy subjects.
    Intervention: Behavioral: Imitate Therapy
Duncan ES, Schmah T, Small SL. Performance Variability as a Predictor of Response to Aphasia Treatment. Neurorehabil Neural Repair. 2016 Oct;30(9):876-82. doi: 10.1177/1545968316642522. Epub 2016 Apr 6.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Terminated
34
57
January 2012
January 2012   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  1. Single ischemic infarction in the MCA territory involving the cerebral cortex (confirmed by CT or MRI)
  2. Aphasia
  3. Visual attention and language comprehension sufficient to perform imitation fMRI tasks
  4. Right handed (prior to stroke)

Exclusion Criteria:

Exclusions to the study are people with cardiac pacemakers, claustrophobia, neurosurgical clips, or cognitive impairments too severe to permit cooperation with cognitive tasks in an MRI scanner.

Sexes Eligible for Study: All
Child, Adult, Older Adult
No
Contact information is only displayed when the study is recruiting subjects
United States
 
 
NCT00713050
13785A
5R01DC007488-05 ( U.S. NIH Grant/Contract )
No
Not Provided
Not Provided
University of Chicago
University of Chicago
  • National Institute on Deafness and Other Communication Disorders (NIDCD)
  • Shirley Ryan AbilityLab
Principal Investigator: Steven Small, M.D., Ph.D. University of Chicago
University of Chicago
June 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP