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Multidetector Raw CT as a Single Tool in the Setting of Ischemic Stroke (COCASE)

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ClinicalTrials.gov Identifier: NCT00708188
Recruitment Status : Completed
First Posted : July 2, 2008
Last Update Posted : July 26, 2013
Sponsor:
Information provided by (Responsible Party):

June 30, 2008
July 2, 2008
July 26, 2013
March 2008
April 2013   (Final data collection date for primary outcome measure)
Ability of CT to classify the stroke etiology correctly (TOAST classification) in comparison to reference methods (MRA, DUS, TEE) [ Time Frame: classify the stroke etiology ]
Same as current
Complete list of historical versions of study NCT00708188 on ClinicalTrials.gov Archive Site
Ability of CT to detect the source of stroke in each etiological group. Reliability of CT in quantitative measures of artery stenosis, aortic atheroma, heart thrombus, heart tumors). Tolerance of CT [ Time Frame: detect the source of stroke ]
Same as current
Not Provided
Not Provided
 
Multidetector Raw CT as a Single Tool in the Setting of Ischemic Stroke
Evaluation of Multidetector Raw Computerized Tomography in the Etiological Analysis of Acute Ischemic Stroke: the "COCASE" Protocol.
This is a prospective study including acute ischemic stroke patients aged 18 to 90. Multidetector raw CT is performed in acute ischemic stroke patients. Heart, neck vessels and brain arteries are studied during the same acquisition. Results are compared with the standard methods including transesophageal echocardiography (TEE), Doppler ultrasound (DUS) and MR angiography (MRA) of neck vessels. The main criteria is the ability of CT to classify the stroke etiology correctly according to the TOAST classification in comparison with the standard methods.
Not Provided
Interventional
Not Provided
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
Ischemic Stroke
Device: Multidetector raw CT
Multidetector raw CT
Experimental: Multidetector raw CT
Intervention: Device: Multidetector raw CT
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
49
April 2013
April 2013   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • Acute (< 1 week) ischemic stroke patient aged 18 to 90
  • Informed consent obtained
  • Presence of health insurance

Exclusion Criteria:

  • Pregnancy or absence of efficient contraceptive method
  • Allergy
  • Allergy to contrast material
  • Asthma
  • Renal failure (blood creatinine > 130 µmoles/l, creatinine clearance < 80 ml/mn according to Cockroft method)
  • Myeloma
  • Hyperthyroidism (uncontrolled)
  • Difficulties to synchronize CT to heart rhythm
  • Contra-indication to TEE or MRI
  • Absence or retirement of informed consent
  • Absence of health insurance
Sexes Eligible for Study: All
18 Years to 90 Years   (Adult, Senior)
No
Contact information is only displayed when the study is recruiting subjects
France
 
 
NCT00708188
2006.431/24
No
Not Provided
Not Provided
Hospices Civils de Lyon
Hospices Civils de Lyon
Not Provided
Principal Investigator: DOUEK Philippe, MD Hospices Civils de Lyon
Hospices Civils de Lyon
July 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP