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Sentinel Surveillance of Malnutrition, Niger

This study has been completed.
Sponsor:
Collaborators:
Ministry of Health, Niger
Medecins Sans Frontieres
Information provided by:
Epicentre
ClinicalTrials.gov Identifier:
NCT00682708
First received: March 26, 2008
Last updated: May 21, 2008
Last verified: May 2008
History of Changes

March 26, 2008
May 21, 2008
August 2006
March 2008   (final data collection date for primary outcome measure)
weight-for-height in children 6 to 60 mo of age [ Time Frame: 8 months ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT00682708 on ClinicalTrials.gov Archive Site
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Sentinel Surveillance of Malnutrition, Niger
Sentinel Surveillance of Acute Malnutrition in the Region of Maradi, Niger, Children Under 5: Impact of a Preventive Intervention

Malnutrition is a critical public health problem in developing countries. Malnutrition may be linked to more than one half of the deaths in children under 5 years old. In July 2001, after an intervention related to a measles epidemic, Medecins sans Frontieres-France opened a nutritional program in Maradi, in the South of Niger. The introduction of ready to use therapeutic foods (RUTF), in particular Plumpy'Nut (Nutriset, France) allowed for the treatment of the majority of children at their homes using ambulatory treatment. Children with complicated cases were cared for in an inpatient center. With ambulatory treatment the number of children cared for in the MSF program reached close to 70000 in 2006.

This study aimed to assess the effect of a 3-month distribution of RUTF in the context of a preventative supplementary feeding program. The primary hypotheses were that short-term RUTF supplementation at the village-level would prevent declines in weight-for-height and reduce the incidence of wasting in children 6 to 60 mo of age over a period of 8 mo. Because RUTF may have additional health effects, the intervention effect on height-for-age, stunting, mortality and morbidity from malaria, diarrhea, and respiratory infection were also examined.
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Interventional
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Primary Purpose: Prevention
Malnutrition
  • Dietary Supplement: PlumpyNut
  • Dietary Supplement: PlumpyDoz
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Isanaka S, Nombela N, Djibo A, Poupard M, Van Beckhoven D, Gaboulaud V, Guerin PJ, Grais RF. Effect of preventive supplementation with ready-to-use therapeutic food on the nutritional status, mortality, and morbidity of children aged 6 to 60 months in Niger: a cluster randomized trial. JAMA. 2009 Jan 21;301(3):277-85. doi: 10.1001/jama.2008.1018.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
Not Provided
March 2008
March 2008   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • All children resident in randomized villages 6-59 months

Exclusion Criteria:

  • N/A
Both
6 Months to 59 Months
Yes
Contact information is only displayed when the study is recruiting subjects
Not Provided
 
NCT00682708
07056
No
Rebecca Freeman Grais, epidemiologist, Epicentre
Epicentre
  • Ministry of Health, Niger
  • Medecins Sans Frontieres
Principal Investigator: Rebecca F Grais Epicentre
Epicentre
May 2008

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP