Preventing HIV/Aids in Drug Abusing Youth

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00680719
Recruitment Status : Completed
First Posted : May 20, 2008
Last Update Posted : August 5, 2014
National Institute on Drug Abuse (NIDA)
Information provided by (Responsible Party):
Oregon Research Institute

May 16, 2008
May 20, 2008
August 5, 2014
June 2004
June 2013   (Final data collection date for primary outcome measure)
Changes in adolescent's substance use. [ Time Frame: 12 months ]
Same as current
Complete list of historical versions of study NCT00680719 on Archive Site
Changes in HIV risk behaviors. [ Time Frame: 12 months ]
Same as current
Not Provided
Not Provided
Preventing HIV/Aids in Drug Abusing Youth
Preventing HIV/Aids in Tx-Resistant Drug-Abusing Youth
This project involves two studies focusing on the engagement and treatment of adolescents diagnosed with substance use disorders. Study 1 will evaluate a promising parent-based engagement intervention, Community Reinforcement Training, designed to facilitate the entry of resistant drug-abusing adolescents in treatment. The approach will be compared with an Engagement As Usual intervention condition. Study 2 involves a controlled clinical trial evaluating the efficacy of an HIV/AIDS prevention intervention embedded in family-based drug abuse treatment for reducing HIV/AIDS risk behaviors and substance use. Adolescents who are successfully engaged in treatment through Study 1 will be randomly assigned to receive either family therapy alone or family therapy with the integrated HIV/AIDS prevention intervention. Both studies are being conducted in Portland, Oregon.
Not Provided
Phase 1
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
HIV Infections
  • Behavioral: IBFT /HIV prevention
    Integrated Behavioral and Family Therapy (IBGT) with HIV prevention.
  • Behavioral: IBFT
    Integrated Behavioral and Family Therapy (IBFT).
  • Active Comparator: 1
    Family Therapy plus HIV prevention
    Intervention: Behavioral: IBFT /HIV prevention
  • Active Comparator: 2
    Family Therapy only.
    Intervention: Behavioral: IBFT
Not Provided

*   Includes publications given by the data provider as well as publications identified by Identifier (NCT Number) in Medline.
June 2013
June 2013   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • Parents have an adolescent in the ages of 15-20 years.
  • Have had contact with the adolescent on at least 40% of the past 90 days.
  • Have some knowledge or evidence that the adolescent would meet DSM-IV diagnostic criteria for a substance abuse disorder.
  • Adolescent has explicitly refused to attend any intake or therapy sessions.
  • All parents' efforts to enter adolescent into treatment have failed, despite therapist's assistance.
  • Residence in Portland vicinity.
  • Sufficient residential stability to permit probable contact at follow-up. (e.g. not homeless at time of intake)

Exclusion Criteria:

  • Evidence of psychotic or organic state of sufficient severity to interfere with understanding of study instruments and procedures.
  • Adolescent has received residential drug treatment longer than a 2-week period in the past 90 days.
Sexes Eligible for Study: All
15 Years to 20 Years   (Child, Adult)
Contact information is only displayed when the study is recruiting subjects
United States
Not Provided
Not Provided
Oregon Research Institute
Oregon Research Institute
National Institute on Drug Abuse (NIDA)
Principal Investigator: Holly B Waldron, Ph.D. Oregon Research Institute
Oregon Research Institute
August 2014

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP