CANDIS-II: Evaluation of the Cognitive-behavioral Treatment Programme CANDIS (CANDIS-II)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00673647
Recruitment Status : Unknown
Verified August 2009 by Technische Universität Dresden.
Recruitment status was:  Active, not recruiting
First Posted : May 7, 2008
Last Update Posted : August 26, 2009
Federal Ministry of Health
Information provided by:
Technische Universität Dresden

May 1, 2008
May 7, 2008
August 26, 2009
May 2008
October 2009   (Final data collection date for primary outcome measure)
abstinence, defined as no evidence of cannabis use during the past 4 weeks as evidenced by self report and a negative urine screen; number of times a cannabis product was used in the past 4 weeks; retention rate [ Time Frame: at the end of treatment ]
Same as current
Complete list of historical versions of study NCT00673647 on Archive Site
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CANDIS-II: Evaluation of the Cognitive-behavioral Treatment Programme CANDIS
Evaluation of the Cognitive-behavioral Treatment Programme CANDIS in the German Outpatient Treatment Service System (CANDIS-II)
The purpose of this study is to evaluate the effectiveness of the cognitive-behavioral treatment program CANDIS among n=450 patients with cannabis use disorders in a mulicenter randomized-controlled clinical trial (n=11 outpatient treatment centers).
Not Provided
Phase 3
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Cannabis Use Disorders
Behavioral: Cognitive-behavioral treatment
10 sessions of individual psychotherapy including cognitive-behavioral treatment, motivational enhancement and a psychosocial problem training.
Other Name: delayed treatment control group
  • Experimental: 1
    Individual psychotherapy including cognitive behavioral components, motivational interviewing techniques and case management
    Intervention: Behavioral: Cognitive-behavioral treatment
  • No Intervention: 2
    Delayed treatment control group
Hoch E, Bühringer G, Pixa A, Dittmer K, Henker J, Seifert A, Wittchen HU. CANDIS treatment program for cannabis use disorders: findings from a randomized multi-site translational trial. Drug Alcohol Depend. 2014 Jan 1;134:185-193. doi: 10.1016/j.drugalcdep.2013.09.028. Epub 2013 Oct 8.

*   Includes publications given by the data provider as well as publications identified by Identifier (NCT Number) in Medline.
Unknown status
Same as current
October 2009
October 2009   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • motivation to change cannabis use
  • age 16 or older
  • current (12 mth) regular cannabis use (at least 2 days a week)
  • informed consent to the study procedures and assessments

Exclusion Criteria:

  • current alcohol or any illicit drug dependence syndrome according to DSM-IV other than due to cannabis
  • lifetime history of any psychotic disorder
  • current severe episode of Major depression
  • current panic-agoraphobic disorder (severe)
  • severe learning disability, brain damage or pervasive developmental disorder
  • currently acute suicidality
  • not fluent in german language
  • any other current treatment for cannabis use disorders
Sexes Eligible for Study: All
16 Years and older   (Child, Adult, Older Adult)
Contact information is only displayed when the study is recruiting subjects
Not Provided
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PhD Eva Hoch, Technische Universitaet Dresden
Technische Universität Dresden
Federal Ministry of Health
Study Director: Hans-Ulrich Wittchen, PhD Technische Universitaet Dresden
Study Director: Gerhard Buehringer, PhD Technische Universitaet Dresden
Principal Investigator: Eva Hoch, PhD Technische Universitaet Dresden
Technische Universität Dresden
August 2009

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP