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The Role of Central Serotonergic and Adrenergic Systems in the Effectiveness of DNIC (Diffuse Noxious Inhibitory Control

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00660751
First Posted: April 17, 2008
Last Update Posted: October 11, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
d_yarnitsky, Rambam Health Care Campus
April 15, 2008
April 17, 2008
October 11, 2017
August 2007
April 2012   (Final data collection date for primary outcome measure)
level of DNIC [ Time Frame: 1 week ]
Same as current
Complete list of historical versions of study NCT00660751 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
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The Role of Central Serotonergic and Adrenergic Systems in the Effectiveness of DNIC (Diffuse Noxious Inhibitory Control
The Role of Central Serotonergic and Adrenergic Systems in the Effectiveness of DNIC (Diffuse Noxious Inhibitory Control
The role of central serotonergic and adrenergic systems in the effectiveness of DNIC (Diffuse Noxious Inhibitory Control) will be tested before and after taking Duloxetine and Placebo in a double blind study.
Not Provided
Interventional
Not Provided
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Triple (Participant, Investigator, Outcomes Assessor)
Primary Purpose: Basic Science
Healthy
Drug: Duloxetine
SNRIs
  • Active Comparator: 1
    Intervention: Drug: Duloxetine
  • Placebo Comparator: 2
    Intervention: Drug: Duloxetine
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
64
April 2012
April 2012   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • Healthy volunteers
  • age 18-80
  • no chronic disease

Exclusion Criteria:

  • Subjects who suffer from chronic pain / pain syndrome
  • use of anti-depressant or anti-psychotic drugs
  • food/ drugs sensitivity
  • breast feeding
Sexes Eligible for Study: All
18 Years to 80 Years   (Adult, Senior)
Yes
Contact information is only displayed when the study is recruiting subjects
Israel
 
 
NCT00660751
DNIC01CTIL
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Not Provided
Not Provided
d_yarnitsky, Rambam Health Care Campus
Rambam Health Care Campus
Not Provided
Principal Investigator: Prof. David Yarnitsky
Rambam Health Care Campus
October 2017

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP