Analysis of the Potentially Parasitocidal Effect of a Long Term Chemotherapy With Benzimidazoles

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.

Verified April 2008 by University of Zurich.
Recruitment status was: Recruiting

Sponsor:

Information provided by:

University of Zurich

ClinicalTrials.gov Identifier:

NCT00658294

First received: April 8, 2008

Last updated: April 11, 2008

Last verified: April 2008

History of Changes

Tracking Information

First Received Date ^ICMJE

April 8, 2008

Last Updated Date

April 11, 2008

Start Date ^ICMJE

January 2008

Primary Completion Date

Not Provided

Current Primary Outcome Measures ^ICMJE

Not Provided

Original Primary Outcome Measures ^ICMJE

Not Provided

Change History

No Changes Posted

Current Secondary Outcome Measures ^ICMJE

Not Provided

Original Secondary Outcome Measures ^ICMJE

Not Provided

Current Other Outcome Measures ^ICMJE

Not Provided

Original Other Outcome Measures ^ICMJE

Not Provided

Descriptive Information

Brief Title ^ICMJE

Analysis of the Potentially Parasitocidal Effect of a Long Term Chemotherapy With Benzimidazoles

Official Title ^ICMJE

Analysis of the Potentially Parasitocidal Effect of a Long Term Chemotherapy With Benzimidazoles in Patients With Inoperable Alveolar Echinococcosis Using PET-CT and EmII/3-10 Serology

Brief Summary

The aim of this study is to evaluate PET-CT and EmII/3-10 serology as potential markers to assess the parasitocidal effect of benzimidazoles

Trial with medicinal product

Detailed Description

Not Provided

Study Type ^ICMJE

Observational

Study Design ^ICMJE

Observational Model: Cohort
Time Perspective: Prospective

Target Follow-Up Duration

Not Provided

Biospecimen

Not Provided

Sampling Method

Not Provided

Study Population

Patients with inoperable alveolar echinococchosis

Condition ^ICMJE

Alveolar Echinococcosis

Intervention ^ICMJE

Other: Stop treatment

Study Groups/Cohorts

Not Provided

Publications *

Ammann RW, Stumpe KD, Grimm F, Deplazes P, Huber S, Bertogg K, Fischer DR, Müllhaupt B. Outcome after Discontinuing Long-Term Benzimidazole Treatment in 11 Patients with Non-resectable Alveolar Echinococcosis with Negative FDG-PET/CT and Anti-EmII/3-10 Serology. PLoS Negl Trop Dis. 2015 Sep 21;9(9):e0003964. doi: 10.1371/journal.pntd.0003964. eCollection 2015.

* Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.

Recruitment Information

Recruitment Status ^ICMJE

Unknown status

Estimated Enrollment ^ICMJE

Estimated Completion Date

January 2009

Primary Completion Date

Not Provided

Eligibility Criteria ^ICMJE

Inclusion criteria:

Patients with inoperable alveolar echinococcosis
With negative PET-CT
EmII/3-10 serology under long-term chemotherapy with benzimidazoles

Exclusion criteria:

Positive PET-CT
Positive EmII-3-10 Serology
No compliance
Reduced life expectancy
Pregnancy

Sex/Gender

Sexes Eligible for Study:

All

Ages

18 Years and older (Adult, Senior)

Accepts Healthy Volunteers

Contacts ^ICMJE

Contact information is only displayed when the study is recruiting subjects

Listed Location Countries ^ICMJE

Switzerland

Removed Location Countries

Administrative Information

NCT Number ^ICMJE

NCT00658294

Other Study ID Numbers ^ICMJE

EK-1351

Has Data Monitoring Committee

U.S. FDA-regulated Product

Not Provided

IPD Sharing Statement

Not Provided

Responsible Party

Beat Müllhaupt, University Hospital Zurich

Study Sponsor ^ICMJE

University of Zurich

Collaborators ^ICMJE

Not Provided

Investigators ^ICMJE

Principal Investigator:

Beat Müllhaupt 01 Studienregister MasterAdmins

UniversitaetsSpital Zuerich

PRS Account

University of Zurich

Verification Date

April 2008

^ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP

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