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Analysis of the Potentially Parasitocidal Effect of a Long Term Chemotherapy With Benzimidazoles

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00658294
First Posted: April 14, 2008
Last Update Posted: October 17, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
University of Zurich
April 8, 2008
April 14, 2008
October 17, 2017
January 2008
December 31, 2012   (Final data collection date for primary outcome measure)
Not Provided
Not Provided
Complete list of historical versions of study NCT00658294 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
Analysis of the Potentially Parasitocidal Effect of a Long Term Chemotherapy With Benzimidazoles
Analysis of the Potentially Parasitocidal Effect of a Long Term Chemotherapy With Benzimidazoles in Patients With Inoperable Alveolar Echinococcosis Using PET-CT and EmII/3-10 Serology

The aim of this study is to evaluate PET-CT and EmII/3-10 serology as potential markers to assess the parasitocidal effect of benzimidazoles

  • Trial with medicinal product
Not Provided
Observational
Observational Model: Cohort
Time Perspective: Prospective
Not Provided
Not Provided
Non-Probability Sample
Patients with inoperable alveolar echinococchosis
Alveolar Echinococcosis
Other: Stop treatment
Not Provided
Ammann RW, Stumpe KD, Grimm F, Deplazes P, Huber S, Bertogg K, Fischer DR, Müllhaupt B. Outcome after Discontinuing Long-Term Benzimidazole Treatment in 11 Patients with Non-resectable Alveolar Echinococcosis with Negative FDG-PET/CT and Anti-EmII/3-10 Serology. PLoS Negl Trop Dis. 2015 Sep 21;9(9):e0003964. doi: 10.1371/journal.pntd.0003964. eCollection 2015.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
34
December 31, 2012
December 31, 2012   (Final data collection date for primary outcome measure)

Inclusion criteria:

  • Patients with inoperable alveolar echinococcosis
  • With negative PET-CT
  • EmII/3-10 serology under long-term chemotherapy with benzimidazoles

Exclusion criteria:

  • Positive PET-CT
  • Positive EmII-3-10 Serology
  • No compliance
  • Reduced life expectancy
  • Pregnancy
Sexes Eligible for Study: All
18 Years and older   (Adult, Senior)
No
Contact information is only displayed when the study is recruiting subjects
Switzerland
 
 
NCT00658294
EK-1351
No
Not Provided
Plan to Share IPD: No
University of Zurich
University of Zurich
Not Provided
Principal Investigator: Beat Müllhaupt 01 Studienregister MasterAdmins UniversitaetsSpital Zuerich
University of Zurich
October 2017