Analysis of the Potentially Parasitocidal Effect of a Long Term Chemotherapy With Benzimidazoles
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ClinicalTrials.gov Identifier: NCT00658294 |
Recruitment Status :
Completed
First Posted : April 14, 2008
Last Update Posted : October 17, 2017
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Sponsor:
University of Zurich
Information provided by (Responsible Party):
University of Zurich
Tracking Information | ||||
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First Submitted Date | April 8, 2008 | |||
First Posted Date | April 14, 2008 | |||
Last Update Posted Date | October 17, 2017 | |||
Actual Study Start Date | January 2008 | |||
Actual Primary Completion Date | December 31, 2012 (Final data collection date for primary outcome measure) | |||
Current Primary Outcome Measures | Not Provided | |||
Original Primary Outcome Measures | Not Provided | |||
Change History | ||||
Current Secondary Outcome Measures | Not Provided | |||
Original Secondary Outcome Measures | Not Provided | |||
Current Other Pre-specified Outcome Measures | Not Provided | |||
Original Other Pre-specified Outcome Measures | Not Provided | |||
Descriptive Information | ||||
Brief Title | Analysis of the Potentially Parasitocidal Effect of a Long Term Chemotherapy With Benzimidazoles | |||
Official Title | Analysis of the Potentially Parasitocidal Effect of a Long Term Chemotherapy With Benzimidazoles in Patients With Inoperable Alveolar Echinococcosis Using PET-CT and EmII/3-10 Serology | |||
Brief Summary | The aim of this study is to evaluate PET-CT and EmII/3-10 serology as potential markers to assess the parasitocidal effect of benzimidazoles
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Detailed Description | Not Provided | |||
Study Type | Observational | |||
Study Design | Observational Model: Cohort Time Perspective: Prospective |
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Target Follow-Up Duration | Not Provided | |||
Biospecimen | Not Provided | |||
Sampling Method | Non-Probability Sample | |||
Study Population | Patients with inoperable alveolar echinococchosis | |||
Condition | Alveolar Echinococcosis | |||
Intervention | Other: Stop treatment | |||
Study Groups/Cohorts | Not Provided | |||
Publications * | Ammann RW, Stumpe KD, Grimm F, Deplazes P, Huber S, Bertogg K, Fischer DR, Müllhaupt B. Outcome after Discontinuing Long-Term Benzimidazole Treatment in 11 Patients with Non-resectable Alveolar Echinococcosis with Negative FDG-PET/CT and Anti-EmII/3-10 Serology. PLoS Negl Trop Dis. 2015 Sep 21;9(9):e0003964. doi: 10.1371/journal.pntd.0003964. eCollection 2015. | |||
* Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline. |
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Recruitment Information | ||||
Recruitment Status | Completed | |||
Actual Enrollment |
34 | |||
Original Estimated Enrollment |
30 | |||
Actual Study Completion Date | December 31, 2012 | |||
Actual Primary Completion Date | December 31, 2012 (Final data collection date for primary outcome measure) | |||
Eligibility Criteria | Inclusion criteria:
Exclusion criteria:
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Sex/Gender |
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Ages | 18 Years and older (Adult, Older Adult) | |||
Accepts Healthy Volunteers | No | |||
Contacts | Contact information is only displayed when the study is recruiting subjects | |||
Listed Location Countries | Switzerland | |||
Removed Location Countries | ||||
Administrative Information | ||||
NCT Number | NCT00658294 | |||
Other Study ID Numbers | EK-1351 | |||
Has Data Monitoring Committee | No | |||
U.S. FDA-regulated Product | Not Provided | |||
IPD Sharing Statement |
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Responsible Party | University of Zurich | |||
Study Sponsor | University of Zurich | |||
Collaborators | Not Provided | |||
Investigators |
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PRS Account | University of Zurich | |||
Verification Date | October 2017 |