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Eating Behavior in Adolescents

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT00631644
Recruitment Status : Completed
First Posted : March 10, 2008
Last Update Posted : October 6, 2017
Sponsor:
Information provided by (Responsible Party):
National Institutes of Health Clinical Center (CC) ( Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) )

Tracking Information
First Submitted Date March 7, 2008
First Posted Date March 10, 2008
Last Update Posted Date October 6, 2017
Study Start Date March 5, 2008
Primary Completion Date Not Provided
Current Primary Outcome Measures Not Provided
Original Primary Outcome Measures Not Provided
Change History Complete list of historical versions of study NCT00631644 on ClinicalTrials.gov Archive Site
Current Secondary Outcome Measures Not Provided
Original Secondary Outcome Measures Not Provided
Current Other Pre-specified Outcome Measures Not Provided
Original Other Pre-specified Outcome Measures Not Provided
 
Descriptive Information
Brief Title Eating Behavior in Adolescents
Official Title Eating Behavior in Adolescents
Brief Summary

This study will explore the eating habits of adolescents and determine if eating behavior is linked to genetics.

Healthy adolescents between 13 and 17 years of age may be eligible for this study. Candidates come to the NIH Clinical Center at 8:00 AM to be screened with the following:

  • Medical history and brief physical examination, including height, weight, and body fat measurements. Body fat is measured using a device called a Bod Pod. The adolescent sits inside the device for about 5 minutes and the machine determines body fat by measuring air movement. The adolescent must wear a tight-fitting swimsuit for this test.
  • Urine test to look for sugar or protein in the urine and to test for pregnancy in females.
  • Blood tests for routine chemistries and for gene studies related to eating behaviors.
  • Questionnaires and interviews about the adolescent s general health and eating habits.
  • Acclimatization to test meal conditions for the study. The adolescent is given a breakfast shake to drink.

Participants come to the NIH Clinical Center at 10:30 AM for laboratory meal testing. At this visit, the adolescent does the following:

  • Eats food from a buffet of everyday foods that most kids eat.
  • Fills out questionnaires.
  • Tastes and rates the flavor of a variety of snack foods.
Detailed Description Little is known about the eating behaviors that place adolescents at heightened risk for overweight. In the proposed study, we aim to investigate the role that eating behaviors and genes may play in the development of overweight. Participants will be adolescent girls and boys from a racially/ethnically diverse sample of adolescents from the DC Metro community. Adolescent eating behavior will be observed during laboratory test meals. Adolescents will be provided with a large buffet of foods or a standard meal and instructed to eat until you are no longer hungry. Thirty minutes later, they will taste and rate a variety of highly palatable snack foods. Blood tests will be conducted to examine genes related to eating behavior. Assessments also will include affective states, degree of hunger, degree of fullness, body image satisfaction, disordered eating attitudes and behaviors, and measures of interpersonal interactions.
Study Type Observational
Study Design Time Perspective: Prospective
Target Follow-Up Duration Not Provided
Biospecimen Not Provided
Sampling Method Not Provided
Study Population Not Provided
Condition
  • Overweight
  • Eating Behavior
  • Binge Eating
Intervention Not Provided
Study Groups/Cohorts Not Provided
Publications *

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruitment Information
Recruitment Status Completed
Actual Enrollment
 (submitted: April 19, 2014)
301
Original Enrollment
 (submitted: March 7, 2008)
200
Study Completion Date September 8, 2015
Primary Completion Date Not Provided
Eligibility Criteria
  • INCLUSION CRITERIA:

Volunteers will qualify for participation in the study if they meet the following criteria:

  1. <TAB>Age 13-17 years.
  2. <TAB>Good general health as indicated by medical history and physical examination.
  3. <TAB>Negative urine glucose and normal electrolytes, hepatic, and thyroid function.
  4. <TAB>For the fMRI portion only: right handedness (required for standardization of responses).
  5. <TAB>For the fMRI portion only: female.
  6. <TAB>For the fMRI portion only: overweight (BMI greater than or equal to 85th percentile for age and sex).

EXCLUSION CRITERIA:

Volunteers will be excluded if they have any of the following:

  1. <TAB>Medical problem likely to affect caloric intake.
  2. <TAB>History of any condition including psychiatric disorders in either child or their responsible parent that in the opinion of the investigators would impede competence to sign consent, interfere with adherence to procedures, or possibly hinder completion of the study.
  3. <TAB>Pregnancy.
  4. <TAB>Use of medication likely to affect caloric intake.
  5. <TAB>History of significant neurological injury or insult.
  6. <TAB>For the fMRI portion only: braces (or other metal) that would interfere with the fMRI procedure.
  7. <TAB>For the fMRI portion only: non-native English speakers (required for standardization of responses).
Sex/Gender
Sexes Eligible for Study: All
Ages 13 Years to 17 Years   (Child)
Accepts Healthy Volunteers Yes
Contacts Contact information is only displayed when the study is recruiting subjects
Listed Location Countries United States
Removed Location Countries  
 
Administrative Information
NCT Number NCT00631644
Other Study ID Numbers 080085
08-CH-0085
Has Data Monitoring Committee Not Provided
U.S. FDA-regulated Product Not Provided
IPD Sharing Statement Not Provided
Responsible Party National Institutes of Health Clinical Center (CC) ( Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) )
Study Sponsor Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Collaborators Not Provided
Investigators
Principal Investigator: Jack A Yanovski, M.D. Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
PRS Account National Institutes of Health Clinical Center (CC)
Verification Date September 8, 2015