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Family Study of Lymphoproliferative Disorders

This study is currently recruiting participants.
Verified September 2016 by Susan Slager, Mayo Clinic
Sponsor:
ClinicalTrials.gov Identifier:
NCT00626496
First Posted: February 29, 2008
Last Update Posted: September 14, 2016
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
Collaborator:
National Cancer Institute (NCI)
Information provided by (Responsible Party):
Susan Slager, Mayo Clinic
February 20, 2008
February 29, 2008
September 14, 2016
April 2004
July 2020   (Final data collection date for primary outcome measure)
Risk of blood or lymphoma [ Time Frame: Ongoing ]
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Complete list of historical versions of study NCT00626496 on ClinicalTrials.gov Archive Site
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Family Study of Lymphoproliferative Disorders
Genetic Epidemiology of Lymphoproliferative Disorders
Blood and lymph node cancers can begin in either the lymphatic tissues (as in the case of lymphoma) or in the bone marrow (as with leukemia and myeloma), and they all are involved with the uncontrolled growth of white blood cells. There are many subtypes of these cancers, e.g., chronic lymphocytic leukemia and non-Hodgkin lymphoma. Since there is evidence that these cancers cluster in families, this study aims to understand how genetics and environmental exposures contribute to the development of these cancers.
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Observational
Observational Model: Family-Based
Time Perspective: Prospective
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Retention:   Samples With DNA
Description:
We will collect blood samples from patients and their relatives for DNA and cytogenetic studies. A one time blood draw of 50 cc will be done.
Non-Probability Sample
Adults over the age of 18 who have a family history of a blood or lymph node disorder.
  • Lymphoma, Non-Hodgkin
  • Leukemia, Lymphocytic, Chronic, B-Cell
  • Lymphoma, B-Cell
  • Monoclonal B-Cell Lymphocytosis
  • Multiple Myeloma
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
2000
July 2020
July 2020   (Final data collection date for primary outcome measure)
At least 2 living, blood related relatives, affected with a lymphoproliferative disorder.
Sexes Eligible for Study: All
18 Years to 100 Years   (Adult, Senior)
Yes
Contact: Catie Erding 1-855-899-0693 Erding.Catherine@mayo.edu
United States
 
 
NCT00626496
489-04
U01CA118444 ( U.S. NIH Grant/Contract )
No
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Susan Slager, Mayo Clinic
Mayo Clinic
National Cancer Institute (NCI)
Principal Investigator: Susan Slager, Ph.D. Mayo Clinic
Mayo Clinic
September 2016