We updated the design of this site on September 25th. Learn more.
Show more
ClinicalTrials.gov
ClinicalTrials.gov Menu

Pre-operative Evaluation of Kidney & Pancreas Transplant Patients

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified August 2011 by University of Nebraska.
Recruitment status was:  Active, not recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT00580437
First Posted: December 24, 2007
Last Update Posted: August 3, 2011
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
University of Nebraska
December 17, 2007
December 24, 2007
August 3, 2011
April 2003
March 2012   (Final data collection date for primary outcome measure)
Provide a higher sensitivity required to adequately assess risks in the pancreas/ kidney transplant evaluation [ Time Frame: I year ]
Same as current
Complete list of historical versions of study NCT00580437 on ClinicalTrials.gov Archive Site
Eliminate the need for costly and invasive additional procedures [ Time Frame: 1 year ]
Same as current
Not Provided
Not Provided
 
Pre-operative Evaluation of Kidney & Pancreas Transplant Patients
The Analysis of Data Collected During Angiography and Dobutamine Stress Contrast Echocardiograms in the Pre-Evaluation of Kidney and Pancreas Transplant Patients
Examine the clinical utility of the dobutamine stress contrast echoes and angiograms obtained routinely in the evaluation of patients prior to kidney or pancreas transplantation.
Although there is an increasing quantity of data demonstrating the value of stress echo in risk stratifying patients for cardiac risk prior to major non-cardiac surgery, the current clinical practice utilized for assessing patients being evaluated for kidney or pancreas transplantation is both a stress echocardiogram and a coronary angiogram. This gap in opinion appears to be a concern on the part of both nephrologists, endocrinologists, and surgeons that the stress echocardiogram may miss significant angiographic disease that could result in major post-operative complications in this high-risk subgroup of patients (unstable angina, non-fatal infarction, or death).
Interventional
Not Provided
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
  • Kidney Transplantation
  • Pancreas Transplantation
Procedure: Dobutamine Stress Echocardiogram
stress echocardiograms involving the use of intravenous Optison or Definity contrast agents to improve endocardial definition
Other Names:
  • Definity
  • Optison
Experimental: Arm 1
stress echocardiograms involving the use of intravenous Optison or Definity contrast agents to improve endocardial definition
Intervention: Procedure: Dobutamine Stress Echocardiogram
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Unknown status
150
April 2012
March 2012   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • Patients who are being evaluated for a kidney and or pancreas transplant and scheduled for a dobutamine stress echocardiogram and a coronary angiogram will be eligible to participate

Exclusion Criteria:

  • Patients with unstable angina at the time of their evaluation, or who have a severe underlying cardiomyopathy or valve disease will be excluded.
Sexes Eligible for Study: All
19 Years and older   (Adult, Senior)
No
Contact information is only displayed when the study is recruiting subjects
United States
 
 
NCT00580437
142-03-FB
Yes
Not Provided
Not Provided
Thomas R Porter, Professor of Medicine, University of Nebraska Medical Center
University of Nebraska
Not Provided
Principal Investigator: Thomas R Porter, MD University of Nebraska
University of Nebraska
August 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP