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Sympathetic Innervation of the Heart and Cardiac Resynchronization Therapy(CRT) (PET-CRT)

This study has been withdrawn prior to enrollment.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00567645
First Posted: December 5, 2007
Last Update Posted: May 13, 2016
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
I.C. Van Gelder, University Medical Center Groningen
December 4, 2007
December 5, 2007
May 13, 2016
July 2007
Not Provided
sympathetic innervation in patients with chronic heart failure (CHF) [ Time Frame: 6 months ]
Same as current
Complete list of historical versions of study NCT00567645 on ClinicalTrials.gov Archive Site
NYHA class Echocardiographic parameters: LVEDD, LVESD, LVEF, LVESV,IVMD, and septal to lateral delay Hospitalization for heart failure Maximal oxygen consumption NT pro-BNP changes [ Time Frame: 6 months ]
Same as current
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Not Provided
 
Sympathetic Innervation of the Heart and Cardiac Resynchronization Therapy(CRT)
Identification of the Role of Sympathetic Innervation in Heart Failure Patients Treated With Cardiac Resynchronization Therapy. A Pilot Study
The purpose of this study is to assess whether baseline sympathetic innervation in patients with chronic heart failure (CHF) is predictive for response to cardiac resynchronization therapy (CRT). And to assess whether response to CRT coincides with restoration of regional sympathetic innervation.
Not Provided
Observational
Observational Model: Case Control
Time Perspective: Retrospective
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Non-Probability Sample
chronic heart failure patients with CRT
  • Sympathetic Innervation
  • Chronic Heart Failure
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Withdrawn
0
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Inclusion Criteria:

  • Indication for CRT
  • Stable optimal medication
  • Non ischemic cardiomyopathy

Exclusion Criteria:

  • Age less then 18 years
  • Previous CRT
  • Clinically relevant valvular heart disease or coronary artery disease
  • Acute or chronic infection
  • Untreated clinical hypo- or hyperthyroidism or < 3 months euthyroidism
  • Uncontrolled hypertension, defined as a systolic blood pressure > 160 mm Hg and/or a diastolic blood pressure > 95 mm Hg
  • A concurrent medical condition (i.e. alcohol or drug abuse or a severe progressive extra cardiac disease or M. Parkinson) or is unlikely to comply with the protocol
  • Participation to a previous protocol involving radioactivity in the past year
  • Pregnancy
Sexes Eligible for Study: All
18 Years to 85 Years   (Adult, Senior)
No
Contact information is only displayed when the study is recruiting subjects
Netherlands
 
 
NCT00567645
16716
No
Not Provided
Not Provided
I.C. Van Gelder, University Medical Center Groningen
University Medical Center Groningen
Not Provided
Principal Investigator: Isabelle C. Van Gelder, Prof University Medical Center Groningen, departmen cardiology
University Medical Center Groningen
May 2016