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Proteomics Analysis for Recognition of Acute Cellular Rejection After Lung Transplantation

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ClinicalTrials.gov Identifier: NCT00558597
Recruitment Status : Unknown
Verified September 2008 by Hannover Medical School.
Recruitment status was:  Recruiting
First Posted : November 15, 2007
Last Update Posted : July 21, 2011
Sponsor:
Information provided by:
Hannover Medical School

November 14, 2007
November 15, 2007
July 21, 2011
March 2008
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Complete list of historical versions of study NCT00558597 on ClinicalTrials.gov Archive Site
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Proteomics Analysis for Recognition of Acute Cellular Rejection After Lung Transplantation
Proteomics Analysis for Recognition of Acute Cellular Rejection After Lung Transplantation
In patients with acute rejection after lung transplantation the peptide profile in broncho-alveolar lavage (BAL) and urine should be compared in order to identify a paradigm that allows an non-invasive rejection therapy.
Goal of the study is the establishment of biomarkers for early diagnosis of acute rejection, followed by a late validation of the paradigm with prospectively collected samples, which will be examined blinded.
Observational
Observational Model: Case Control
Time Perspective: Prospective
Not Provided
Retention:   Samples Without DNA
Description:
BAL (broncho alveolar lavage) urine
Probability Sample
patients after lung transplantation
  • Rejection
  • Lung Transplantation
Not Provided
  • 1
    30 patients with stable graft function
  • 2
    30 patients with acute rejection after lung transplantation
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Unknown status
60
Same as current
December 2011
Not Provided

Inclusion Criteria:

  • Patients with stable graft function
  • Patients with acute rejection

Exclusion Criteria:

  • Acute infection
  • BOS
Sexes Eligible for Study: All
18 Years to 70 Years   (Adult, Older Adult)
No
Contact information is only displayed when the study is recruiting subjects
Germany
 
 
NCT00558597
154
No
Not Provided
Not Provided
Hannover Medical School, Medical School
Hannover Medical School
Not Provided
Principal Investigator: Jens Gottlieb, Dr. med. Hannover Medical School
Hannover Medical School
September 2008