A Pilot Study of Functional Optical Coherence Tomography for Ocular Imaging

This study has been completed.
Sponsor:
Collaborator:
Beckman Laser Institute University of California Irvine
Information provided by (Responsible Party):
Beckman Laser Institute and Medical Center, University of California, Irvine
ClinicalTrials.gov Identifier:
NCT00556114
First received: November 7, 2007
Last updated: August 5, 2015
Last verified: August 2015

November 7, 2007
August 5, 2015
January 2007
July 2013   (final data collection date for primary outcome measure)
Medical exam tool [ Time Frame: 24 hours ] [ Designated as safety issue: Yes ]
Optical Coherence Tomography imaging technique of the retina and ability to diagnose and manage many eye diseases
Not Provided
Complete list of historical versions of study NCT00556114 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
A Pilot Study of Functional Optical Coherence Tomography for Ocular Imaging
A Pilot Study of Functional Optical Coherence Tomography for Ocular Imaging

Growing evidence shows that altered blood flow plays a major role in many vision-threatening diseases including glaucoma, diabetic retinopathy, age-related macular degeneration, Central Retinal Vein Occlusion, and Branch Retinal Vein Occlusion. Optical coherence tomography, an established imaging technique use for eye exam in clinical ophthalmology, provides high-resolution cross sectional images of the retina and has increased our ability to understand many eye diseases.

Optical Coherence Tomography is a non-invasive technique use a broadband light source to illuminate the area of study with light in the near infrared spectrum, then obtains static images of tissue structure from interference signals of the back-reflected light.

Optical Coherence Tomography a non-contact, non-invasive means of documenting both tissue structure and blood flow changes in ocular disease and can provide high resolution cross-sectional images of tissue structure, direct visualization of blood flow in blood vessels of the eye.

Observational
Observational Model: Case Control
Time Perspective: Prospective
Not Provided
Not Provided
Non-Probability Sample

Primary care clinic and community sample.

  • Glaucoma
  • Diabetic Retinopathy
  • Age-Related Macular Degeneration
  • Central Retinal Vein Occlusion
  • Branch Retinal Vein Occlusion
Device: Optical Coherence Tomography
Optical Coherence Tomography
Optical Coherence Tomography
Optical Coherence Tomography
Intervention: Device: Optical Coherence Tomography
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
23
July 2013
July 2013   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Adult 18 years and older with normal eye, or has been diagnosed with eye disease.

Exclusion Criteria:

  • Less than 18 years of age.
Both
18 Years and older
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00556114
NIH-LAMMP-2004-3555
No
Beckman Laser Institute and Medical Center, University of California, Irvine
University of California, Irvine
Beckman Laser Institute University of California Irvine
Principal Investigator: Baruch D Kuppermann,, M.D., Ph.D. Ophthamology, University of California,Irvine
Principal Investigator: Zhongping Chen, Ph,D Beckman Laser Institute University of California Irvine
University of California, Irvine
August 2015

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP