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Establishing Effective Screening Methods for Diagnosing Hereditary Nonpolypoisis Colorectal Cancer

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ClinicalTrials.gov Identifier: NCT00516230
Recruitment Status : Unknown
Verified August 2007 by Samsung Medical Center.
Recruitment status was:  Recruiting
First Posted : August 15, 2007
Last Update Posted : August 15, 2007
Sponsor:
Information provided by:

August 13, 2007
August 15, 2007
August 15, 2007
January 2006
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No Changes Posted
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Establishing Effective Screening Methods for Diagnosing Hereditary Nonpolypoisis Colorectal Cancer
Establishing Effective Screening Methods for Diagnosing Hereditary Nonpolypoisis Colorectal Cancer
Correct identification of Lynch syndrome at the time of colorectal cancer presentation is important. We aim to find best ways to screen patients with colorectal cancer in Korea.
Patients with newly diagnoised colorectal cancer will be eligible. They will undergo detailed history taking including family history, and molecular stuidies including microsatellite instability test and immunohistochemistry for DNA mismatch repair protein with pre-selection. Any abnormal finding in molecular stuides will be offered genetic testing (after testing methylation status for patients with abnormalities in MLH1).
Observational
Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Longitudinal
Time Perspective: Prospective
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Colonic Neoplasms
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Unknown status
200
December 2011
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Inclusion Criteria:

  • Colorectal cancer

Exclusion Criteria:

  • Histology showing other than adenocarcinoma
Sexes Eligible for Study: All
Child, Adult, Senior
No
Contact information is only displayed when the study is recruiting subjects
Korea, Republic of
 
 
NCT00516230
SMC-2007-04-080
Yes
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Samsung Medical Center
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Principal Investigator: Dong Kyung Chang, M.D. Ph.D Division of Gastroenterology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine
Samsung Medical Center
August 2007