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Explanted Lung Tissues With Pulmonary Fibrosis

This study is currently recruiting participants.
Verified September 2016 by University of Chicago
Sponsor:
ClinicalTrials.gov Identifier:
NCT00515567
First Posted: August 13, 2007
Last Update Posted: September 21, 2016
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
Information provided by (Responsible Party):
University of Chicago
August 9, 2007
August 13, 2007
September 21, 2016
February 2006
December 2018   (Final data collection date for primary outcome measure)
assess fibroblasts and cytokines associated with pulmonary fibrosis [ Time Frame: 12/2013 ]
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Complete list of historical versions of study NCT00515567 on ClinicalTrials.gov Archive Site
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Explanted Lung Tissues With Pulmonary Fibrosis
Utilization of Explanted Lungs for Isolation of Tissue Samples and Primary Cell Lines to Study Pulmonary Fibrosis
The goal of this study is to use the tissues from the explanted lungs in order to better study the cause of pulmonary fibrosis at a cellular level.

Pulmonary Fibrosis involves scarring of the lung. Gradually, the air sacs of the lungs become replaced by fibrotic tissue. The most current thinking is that the fibrotic process is a reaction to tiny injury to the lung. When the scar forms, the tissue becomes thicker causing a permanent loss of the tissue's ability to carry oxygen into the bloodstream.

We need to obtain lung tissue from patients without pulmonary fibrosis and compare it to lung tissue from patients with pulmonary fibrosis.

Observational
Observational Model: Case-Only
Time Perspective: Prospective
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Retention:   Samples With DNA
Description:
explanted lung tissue
Non-Probability Sample
Subjects listed for lung transplant
Pulmonary Fibrosis
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
90
December 2019
December 2018   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • all patients awaiting lung transplant

Exclusion Criteria:

  • all who will not give consent
Sexes Eligible for Study: All
18 Years and older   (Adult, Senior)
No
Contact: Edward Garrity, MD egarrity@medicine.bsd.uchicago.edu
United States
 
 
NCT00515567
14514A
No
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University of Chicago
University of Chicago
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Principal Investigator: Edward Garrity, MD University of Chicago
University of Chicago
September 2016