Therapeutic Massage for Generalized Anxiety Disorder (CALM)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00515242
Recruitment Status : Completed
First Posted : August 13, 2007
Last Update Posted : October 13, 2017
National Center for Complementary and Integrative Health (NCCIH)
Information provided by (Responsible Party):
Kaiser Permanente

August 9, 2007
August 13, 2007
October 13, 2017
September 2007
October 2008   (Final data collection date for primary outcome measure)
anxiety [ Time Frame: 6 months ]
Same as current
Complete list of historical versions of study NCT00515242 on Archive Site
worry, depression, disability [ Time Frame: 6 months ]
Same as current
Not Provided
Not Provided
Therapeutic Massage for Generalized Anxiety Disorder
Therapeutic Massage for Generalized Anxiety Disorder
The purpose of this study is to compare the relative effectiveness of three relaxation treatments (therapeutic massage, thermotherapy, and time in a relaxing environment) in reducing anxiety in persons with Generalized Anxiety Disorder.
Anxiety and stress are costly problems that afflict millions of American adults. Together, they are among the most common reasons for which adults use complementary and alternative medical (CAM) therapies as well as more conventional relaxation therapies. Although massage is one of the most popular CAM treatments for anxiety, its effectiveness for this problem has never been rigorously evaluated. This study is designed to evaluate the effectiveness of massage as a treatment for a diagnosed anxiety disorder. Massage will be compared with two other relaxing treatments: thermotherapy and time in a relaxing environment, which reflect the types of activities that persons with anxiety might try to relieve their symptoms.
Phase 1
Phase 2
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Outcomes Assessor)
Primary Purpose: Treatment
Generalized Anxiety Disorder
  • Behavioral: massage
    therapeutic massage
  • Behavioral: thermotherapy
    heat therapy
  • Behavioral: relaxing environment
    time in a relaxing environment
  • Experimental: 1
    Therapeutic massage
    Intervention: Behavioral: massage
  • Active Comparator: 2
    Intervention: Behavioral: thermotherapy
  • Placebo Comparator: 3
    Intervention: Behavioral: relaxing environment
Not Provided

*   Includes publications given by the data provider as well as publications identified by Identifier (NCT Number) in Medline.
August 2009
October 2008   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • Member of Group Health, Seattle metropolitan area
  • Generalized Anxiety Disorder confirmed by SCID
  • At least moderate anxiety

Exclusion Criteria:

  • Serious mental health co-morbidity
  • Any life threatening condition
  • Currently receiving psychotherapy
  • Substantial alcohol use
  • Contraindications for massage
Sexes Eligible for Study: All
18 Years to 70 Years   (Adult, Older Adult)
Contact information is only displayed when the study is recruiting subjects
United States
R21AT002560( U.S. NIH Grant/Contract )
R21AT002560 ( U.S. NIH Grant/Contract )
Not Provided
Not Provided
Kaiser Permanente
Kaiser Permanente
National Center for Complementary and Integrative Health (NCCIH)
Principal Investigator: Karen J. Sherman, PhD, MPH Group Health
Kaiser Permanente
October 2017

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP