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MAGIC Cell-5-Combicytokine Trial (MAGIC Cell-5)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00501917
Recruitment Status : Unknown
Verified July 2007 by Seoul National University Hospital.
Recruitment status was:  Recruiting
First Posted : July 16, 2007
Last Update Posted : July 16, 2007
Information provided by:
Seoul National University Hospital

July 13, 2007
July 16, 2007
July 16, 2007
March 2007
Not Provided
change of left ventricular ejection fraction measured by cardiac MRI [ Time Frame: 6, 12, and 24month ]
Same as current
No Changes Posted
wall motion score index exercise capacity BNP [ Time Frame: 6,12, 24month ]
Same as current
Not Provided
Not Provided
MAGIC Cell-5-Combicytokine Trial
Single Center, Prospective, Randomized, Partly-Double Blinded, Controlled Trial to Assess the Safety and Feasibility of Intracoronary Cell Infusion Mobilized With G-CSF and Darbepoetin and Their Effects on Improvement of Cardiac Function in Patients With Myocardial Infarction: Myocardial Regeneration and Angiogenesis in Myocardial Infarction With G-CSF and Erythropoietin Mobilization and Intra-Coronary Cell Infusion –5-Combination Cytokine Therapy Trial
Combination use of darbepoetin and G-CSF will improve left ventricular systolic function in patients with acute myocardial infarction who receive intracoronary infusion of mobilized peripheral blood stem cell in comparison with patient who treated with conventional measures and who received intracoronary infusion of mobilized peripheral blood stem cell by G-CSF alone.
Not Provided
Phase 2
Phase 3
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double
Primary Purpose: Treatment
Acute Myocardial Infarction
Drug: G-CSF with/without darbepoetin, peripheral blood stem cell infusion
Not Provided

*   Includes publications given by the data provider as well as publications identified by Identifier (NCT Number) in Medline.
Unknown status
February 2010
Not Provided

Inclusion Criteria:

  • ST elevation acute myocardial infarction
  • < 80years
  • successful revascularization of culprit vessel

Exclusion Criteria:

  • uncontrolled congestive heart failure
  • uncontrolled myocardial ischemia
  • uncontrolled ventricular arrhythmia
  • malignancy
  • serious hematologic disease
  • chronic renal failure
Sexes Eligible for Study: All
15 Years to 80 Years   (Child, Adult, Senior)
Contact information is only displayed when the study is recruiting subjects
Korea, Republic of
MAGIC Cell-5
Not Provided
Not Provided
Not Provided
Seoul National University Hospital
Not Provided
Principal Investigator: Hyo-Soo Kim, MD PhD Seoul National University Hospital
Seoul National University Hospital
July 2007

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP