Comparing Rehabilitation Programs for Patellofemoral Pain Syndrome

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Timothy Uhl, University of Kentucky
ClinicalTrials.gov Identifier:
NCT00445224
First received: March 6, 2007
Last updated: July 30, 2015
Last verified: July 2015

March 6, 2007
July 30, 2015
January 2008
January 2010   (final data collection date for primary outcome measure)
  • Visual Analog Pain Scale (Describing Worst Pain Felt During the Past Week) [ Time Frame: weekly ] [ Designated as safety issue: No ]
    0 to 10 cm line with 0 representing no pain and 10 representing severe pain
  • Subjective Function by Lower Extremity Functional Scale Report Form [ Time Frame: Baseline, Mid-Intervention, and Post-Intervention ] [ Designated as safety issue: No ]
  • Visual Analog Pain Scale [ Time Frame: 8 week ] [ Designated as safety issue: No ]
    Visual analog pain scale at end of intervention. 0 to 10 cm line with 0 representing no pain and 10 representing severe pain
  • Pain on visual analog scale
  • Subjective Function by Lower Extremity Functional Scale report form
Complete list of historical versions of study NCT00445224 on ClinicalTrials.gov Archive Site
  • Strength by Isometric Dynamometer [ Time Frame: Baseline, Mid, and Post-Intervention ] [ Designated as safety issue: No ]
  • Neuromuscular Activity by Surface Electromyographical Amplitude During Stair Descent [ Time Frame: Baseline, Mid and Post-Intervention ] [ Designated as safety issue: No ]
  • Objective Function by Step-down Task for 30 Seconds [ Time Frame: Baseline, Mid, and Post-Intervention ] [ Designated as safety issue: No ]
  • Hip Abduction Strength [ Time Frame: 8 week ] [ Designated as safety issue: No ]
    Side lying Hip Abduction maximal muscular contraction with a hand held dynamometer
  • Strength by isometric dynamometer
  • Neuromuscular activity by surface electromyographical amplitude during stair descent
  • Objective Function by step-down task for 30 seconds
Not Provided
Not Provided
 
Comparing Rehabilitation Programs for Patellofemoral Pain Syndrome
Comparison of Early Hip Strengthening to Early Quadriceps Strengthening in the Treatment of Females With Patellofemoral Pain

Patellofemoral pain syndrome (PFPS) is a common knee disorder affecting physically active people. Despite the growing base of support for the early introduction of hip strengthening exercises into the rehabilitation of PFPS, there have been few randomized clinical trials comparing isolated hip to isolated quadriceps strengthening. The purpose of this study is to determine how different exercises affect pain, strength, muscle activity, and function in female subjects with patellofemoral pain. The researchers hypothesize that females diagnosed with PFPS who initially participate in a hip strengthening program will report a greater perceived level of function, greater strength, less pain, and improved neuromuscular activity than those who participate in a progressive quadriceps strengthening intervention.

Methods: Thirty-three females with PFPS will perform either initial hip strengthening (hip group) or initial quadriceps strengthening (quad group) for 4 weeks, prior to 4 weeks of a similar program of functional weight-bearing exercises. Self-reported pain, function, and functional strength were measured. Isometric strength was assessed for hip abductors, external rotators, and knee extensors. A mixed-model analysis of variance will be used to determine group differences over time.

Interventional
Phase 2
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Crossover Assignment
Masking: Single Blind (Subject)
Primary Purpose: Treatment
Patellofemoral Pain Syndrome
  • Other: Hip Progressive Resistive Exercise
    Hip Progressive Resistance Exercise program will be carried out by subjects under supervision once a week and then performed at home 2 additional times at home without supervision. Exercises focus on strengthening hip abduction ad external rotation musculature.
  • Other: Quad Progressive Resistive Exercises
    Quad Progressive Resistive Exercise program will be carried out by subjects under supervision once a week and then performed at home 2 additional times at home without supervision. Exercises focus on strengthening quadriceps musculature with straight leg raises and quadriceps isometrics.
  • Experimental: Hip Progressive Resistive Exercises
    Exercises targeting hip musculature such as hip abduction and hip external rotation that was progressed by increased resistance following typical progressive resistive exercise approach.
    Intervention: Other: Hip Progressive Resistive Exercise
  • Active Comparator: Quad Progressive Resistive Exercises
    Exercises targeting quadriceps musculature such as quadriceps isometric setting, terminal knee extensions, and straight leg raises that was progressed by increased resistance following typical progressive resistive exercise approach..
    Intervention: Other: Quad Progressive Resistive Exercises
Dolak KL, Silkman C, Medina McKeon J, Hosey RG, Lattermann C, Uhl TL. Hip strengthening prior to functional exercises reduces pain sooner than quadriceps strengthening in females with patellofemoral pain syndrome: a randomized clinical trial. J Orthop Sports Phys Ther. 2011 Aug;41(8):560-70. doi: 10.2519/jospt.2011.3499. Epub 2011 Jun 7. Erratum in: J Orthop Sports Phys Ther. 2011 Sep;41(9):700.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
33
January 2010
January 2010   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • anterior or retropatellar knee pain reported during at least 2 of the following activities: ascending and descending stairs, hopping and running, squatting, kneeling, and prolonged sitting
  • insidious onset of symptoms not related to trauma
  • pain with compression of the patella
  • pain on palpation of the patellar facets

Exclusion Criteria:

  • symptoms present for less than one month
  • clinical evidence of other knee pathology
  • history of recent knee surgery within past one year
  • history of patellar dislocations or subluxations
  • current significant injury affecting other lower extremity joints
Female
15 Years to 35 Years
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00445224
07-0138-F2L
No
Timothy Uhl, University of Kentucky
University of Kentucky
Not Provided
Study Chair: Timothy Uhl, PhD, ATC, PT University of Kentucky
University of Kentucky
July 2015

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP