Comparison of Early and Late Therapy for Adults With Operatively Treated Distal Radius Fractures

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00438308
Recruitment Status : Completed
First Posted : February 22, 2007
Last Update Posted : August 12, 2010
Information provided by:
Massachusetts General Hospital

February 20, 2007
February 22, 2007
August 12, 2010
December 2004
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range of motion in degrees of the wrists [ Time Frame: 6 months ]
range of motion in degrees of the wrists
Complete list of historical versions of study NCT00438308 on Archive Site
  • DASH score [ Time Frame: 6 months ]
  • Likert pain scale [ Time Frame: 6 months ]
  • pinch and grip strength [ Time Frame: 6 months ]
  • Gartland and Werely score [ Time Frame: 6 months ]
  • and Mayo wrist score [ Time Frame: 6 months ]
  • DASH score
  • Likert pain scale
  • pinch and grip strength
  • Gartland and Werely score
  • and Mayo wrist score
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Comparison of Early and Late Therapy for Adults With Operatively Treated Distal Radius Fractures
Prospective Randomized Comparison of Early and Late Wrist Mobilization After Volar Plate Fixation of a Fracture of the Distal Radius
The purpose of the study is to compare two common ways of rehabilitating after surgery for distal radius fractures treated operatively with a volar plate.
Over the last three decades, operative treatment of distal radius fractures has become increasingly common compared to non-operative treatment. Over the last 15 years there has been a trend towards more invasive, internal plate fixation of fractures of the distal radius. One argument in favor of internal fixation for these fractures is that, similar to other periarticular fractures, it would be beneficial to allow early movement of the wrist articulation. There is not, however, any data to support this statement. In fact, data regarding external fixation that either immobilizes the wrist or allows wrist motion suggest that early wrist mobilization is not as important as the overall alignment of the bone in terms of final wrist motion. This question is important in patient care and in decision-making regarding these fractures. Additionally, many companies use this claim as a marketing point in spite of the lack of evidence. We consider that good quality data is needed to determine the answer to this issue and to help to resolve the related problems described above.
Observational Model: Cohort
Time Perspective: Prospective
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Non-Probability Sample
Patients from the MGH Hand and Upper Extremith Service
Distal Radius Fractures
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  • 1
    Subjects who begin therapy immediately after fracture.
  • 2
    Subjects delay therapy for 3 weeks after injury.
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*   Includes publications given by the data provider as well as publications identified by Identifier (NCT Number) in Medline.
Same as current
May 2007
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Inclusion Criteria:

  • Gender: Male or female
  • Age: Older than 18
  • Isolated distal radial fracture
  • Fracture treated with volar plates, stable fixation
  • Initial treatment within 4 weeks of trauma

Exclusion Criteria:

  • Complex fractures that require additional or different material than volar plates
  • Unstable fractures in which early mobilization is contraindicated
Sexes Eligible for Study: All
18 Years and older   (Adult, Senior)
Contact information is only displayed when the study is recruiting subjects
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David C Ring, MD, Massachusetts General Hospital
Massachusetts General Hospital
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Principal Investigator: David Ring, MD, PhD Massachusetts General Hospital
Massachusetts General Hospital
August 2010