First Experimental Study of Transference-Interpretations (FEST)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00423462
Recruitment Status : Completed
First Posted : January 18, 2007
Last Update Posted : August 27, 2007
The Research Council of Norway
Information provided by:
University of Oslo

January 16, 2007
January 18, 2007
August 27, 2007
January 1993
Not Provided
  • The Psychodynamic Functioning Scales (PFS), clinician rated
  • Inventory if Interpersonal Problems-Circumplex version (IIP-C), self-report
Same as current
Complete list of historical versions of study NCT00423462 on Archive Site
  • The Global Assessment of Functioning Scale (GAF)
  • Global Severity Index (GSI) from SCL-90-R
Same as current
Not Provided
Not Provided
First Experimental Study of Transference-Interpretations (FEST)
First Experimental Study of Transference Interpretations (FEST)

Analysis of the ongoing patient-therapist interaction, the transference, is considered a key active ingredient in psychoanalytically oriented psychotherapy and psychoanalysis.However, one century after Sigmund Freuds's famous "Dora" case, the first clinical description of transference, no study of transference interpretations have been published.In the present study 100 out-patients were randomized to receive one year weekly dynamic psychotherapy, with and without transference interpretations. That is, one treatment component,transference interpretations, were added to a comparison condition, therapy of the same format, by the same therapists, but without use of transference interpretation.

All treatment session were audiotaped, and treatment integrity have been carefully checked. Patients were evaluated at treatment termination, one year after treatment termination and three years after treatment termination. Enrollment of patients started january 1993, and all follow-up evaluations completed by December 2005.

This study is designed to measure specific long-term effects of transference interpretations in dynamic psychotherapy, using an experimental dismantling design. One hundred psychiatric out-patients, referred to seven study therapists, to receive exploratory dynamic psychotherapy, were randomized to one year weekly dynamic psychotherapy, with and without transference interpretations.They suffered from mood,anxiety,and personality disorders or interpersonal problems not due to a mental disorder. All treatment sessions were audiotaped and treatment integrity carefully checked.All patients have been evaluated before treatment, after treatment, one year after termination of treatment, and three years after termination of treatment. The main outcome measures were the Psychodynamic Functioning Scales (PFS) and Inventory of Interpersonal Problems-Circumplex version (IIP-C).Chang over time is assessed using linear mixed model analyses.

The main hypothesis is that patients treated with transference interpretations will have a more favourable course over the whole study period of four years.

The second hypothesis is that suitable patients, that is patients with a life long pattern of more mature object relations (QOR) and/or patients without comorbid personality disorders will do better with transference interpretations.

Insight and identification with the therapist will be analyzed as putative mediators of long-term change in interpersonal functioning

Phase 2
Phase 3
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single
Primary Purpose: Treatment
  • Mood Disorders
  • Anxiety Disorders
  • Personality Disorders
Behavioral: Brief dynamic psychotherapy
Not Provided

*   Includes publications given by the data provider as well as publications identified by Identifier (NCT Number) in Medline.
Same as current
December 2005
Not Provided

Inclusion Criteria:

  • Age 20 - 60 years
  • Diagnoses Mood-disorder, non-psychotic
  • Anxiety disorders
  • Personality disorders
  • Interpersonal problems not due to a mental disorder

Exclusion Criteria:

  • Psychotic disorders
  • Bipolar disorder
  • Organic brain disorder
  • Substance abuse
  • Long-term (years) disability
  • Mental retardation
Sexes Eligible for Study: All
20 Years to 60 Years   (Adult)
Contact information is only displayed when the study is recruiting subjects
Not Provided
Not Provided
Not Provided
Not Provided
University of Oslo
The Research Council of Norway
Principal Investigator: Per Høglend, M.D. Ph. D. Department of Psychiatry, Faculty of Medicine, Unoversity of Oslo
University of Oslo
August 2007

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP