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Prognostic Significance of the Baroreflex Sensitivity Changes After Acute Ischemic Stroke

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified July 2008 by Far Eastern Memorial Hospital.
Recruitment status was:  Recruiting
Sponsor:
Information provided by:
Far Eastern Memorial Hospital
ClinicalTrials.gov Identifier:
NCT00422474
First received: January 14, 2007
Last updated: July 8, 2008
Last verified: July 2008

January 14, 2007
July 8, 2008
January 2007
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Complete list of historical versions of study NCT00422474 on ClinicalTrials.gov Archive Site
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Prognostic Significance of the Baroreflex Sensitivity Changes After Acute Ischemic Stroke
Noninvasive Study of the Time Course of Baroreflex Sensitivity 6-Month After Acute Ischemic Stroke and the Relation of Its Changes With Post Stroke Prognosis

After acute stroke, baroreflex sensitivity (BRS) is impaired. This impaired acute stage BRS has been reported to be predictive of worsen outcome years after stroke in general. However, it is not very clear if the impaired acute stroke BRS would actually persist months after the acute stage. It is also not clear that such change, if any, would correlate with the functional outcome or prognosis after stroke.

The trial is to investigate the longitudinal time course of BRS after ischemic stroke up to the 6th month post stroke and to see if there is any correlation of the changes in BRS with the functional outcome parameters using NIHSS and mRS scores throughout this period.

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Observational
Time Perspective: Prospective
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  • Cerebrovascular Accident
  • Baroreflexes
  • Autonomic Nervous System Diseases
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Unknown status
100
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Inclusion Criteria:

  • Baroreflex sensitivity can be done within 72 hours of onset of acute ischemic stroke
  • 50-80 years old
  • Must have either brain CT or brain MRI done

Exclusion Criteria:

  • NIHSS score > 10
  • Patient could not cooperate
  • Unstable vital sign
  • Atrial fibrillation
  • Transient ischemic attack patient
  • Diabetic patient
  • Impaired renal function (Cr > 2.26 mg/dl)
  • Unstable angina, acute myocardiac infarction, cardiomyopathy patients
  • Patient who has known autonomic dysfunction
Sexes Eligible for Study: All
50 Years to 80 Years   (Adult, Senior)
No
Contact information is only displayed when the study is recruiting subjects
Taiwan
 
 
NCT00422474
FEMH-95-C-012
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Dr. Siupak Lee, Far Eastern Memorial Hospital
Far Eastern Memorial Hospital
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Principal Investigator: Siupak Lee, M.D. Far Eastern Memorial Hospital
Far Eastern Memorial Hospital
July 2008

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP