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Insulin Resistance and Hypertensive Disorders in Pregnancy

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT00412230
Recruitment Status : Completed
First Posted : December 18, 2006
Last Update Posted : February 18, 2009
Information provided by:

December 15, 2006
December 18, 2006
February 18, 2009
October 2006
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Complete list of historical versions of study NCT00412230 on ClinicalTrials.gov Archive Site
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Insulin Resistance and Hypertensive Disorders in Pregnancy
The Role of Insulin Resistance in Gestational Hypertension and in Preeclampsia.
The purpose of this study is to determine whether insulin resistance might affect the pathogenesis of hypertensive disorders in pregnancy since midtrimester. Furthermore, markers of vascular and placental injuries, of oxidative stress and inflammation will be evaluated.
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Observational Model: Case Control
Time Perspective: Retrospective
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Non-Probability Sample
pregnant outpatients
  • Hypertension in Pregnancy
  • Diabetes Mellitus in Pregnancy
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  • no treatment
  • 2
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
June 2008
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Inclusion Criteria:

  • PCOS, BMI>/=30
  • previous pregnancy affected by hypertension or gestational diabetes
  • thrombophilia
  • Type I or II diabetes mellitus
  • autoimmune diseases
  • twin pregnancy
  • renal diseases
  • previous pre-eclampsia in relatives
Sexes Eligible for Study: Female
18 Years to 45 Years   (Adult)
Contact information is only displayed when the study is recruiting subjects
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Rosario D'Anna, University of Messina
University of Messina
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Principal Investigator: Rosario D'Anna, Associate Professor University of Messina
University of Messina
February 2009