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The Effect of Ischemic Training on Exercise Endurance

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00333905
First Posted: June 6, 2006
Last Update Posted: February 5, 2009
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
VA Office of Research and Development
June 2, 2006
June 6, 2006
February 5, 2009
March 2006
Not Provided
Exercise duration before and after 12 weeks of training during a submaximal exercise test and distance walked on a 6-minute walk test.
Same as current
Complete list of historical versions of study NCT00333905 on ClinicalTrials.gov Archive Site
Peak cycle ergometer VO2max test before and after training
Same as current
Not Provided
Not Provided
 
The Effect of Ischemic Training on Exercise Endurance
The Effect of Ischemic Training on Exercise Endurance
The purpose of this study is to determine if reducing blood flow to an exercising muscle during exercise training will enhance the training effect on that muscle in people who have limited exercise because of congestive heart failure
The objective of this study is to determine whether reduction of blood flow during stair-stepping and cycling ergometer leg exercise will contribute to an improvement in whole body exercise capacity or submaximal exercise endurance in patients with mild congestive heart failure. Two groups of 25 patients with mild to moderate CHF, aged 30-70, will be trained for 12 weeks. The experimental group will train with pressure cuffs inflated on one thigh and lower leg during exercise. The cuff will be applied on alternate legs during training, such that each leg has the same duration of ischemic training. The control group will train for a similar duration and intensity without pressure cuffs on the legs. Pre and post training measures will include VO2peak, exercise duration at 30% VO2peak, 6 minute walk test, Minnesota Living with Heart Failure questionnaire
Interventional
Not Provided
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single
Primary Purpose: Treatment
  • Heart Failure
  • Congestive Heart Failure
  • Cardiovascular Disease
Procedure: Ischemic exercise training
Not Provided
Loeppky JA, Gurney B, Kobayashi Y, Icenogle MV. Effects of ischemic training on leg exercise endurance. J Rehabil Res Dev. 2005 Jul-Aug;42(4):511-22.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
50
February 2008
Not Provided

Inclusion Criteria:

  • Mild Congestive Heart Failure
  • Must be able to exercise

Exclusion Criteria:

  • Venous or arterial thrombus
  • Lower extremity arthritis
  • Blood clotting abnormalities
  • Claudication
  • Peripheral vascular disease
  • Evidence of deep vein thrombosis on ultrasound
Sexes Eligible for Study: All
30 Years to 71 Years   (Adult, Senior)
No
Contact information is only displayed when the study is recruiting subjects
United States
 
 
NCT00333905
F4096R
Not Provided
Not Provided
Not Provided
Not Provided
VA Office of Research and Development
Not Provided
Principal Investigator: Milton V Icenogle, MD Cardiology Division Chief, Medicine Service VAMC Albuquerque (501) Albuquerque, NM
VA Office of Research and Development
June 2006

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP