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Study of Sildenafil in Patient With Heart Failure.

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ClinicalTrials.gov Identifier: NCT00309816
Recruitment Status : Completed
First Posted : April 3, 2006
Last Update Posted : April 3, 2006
Sponsor:
Information provided by:
Massachusetts General Hospital

March 30, 2006
April 3, 2006
April 3, 2006
December 2001
Not Provided
Patients will have exercise capacity measured by an exercise stress test before and after one dose of sildenafil.
Same as current
No Changes Posted
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Study of Sildenafil in Patient With Heart Failure.
Measurement of the Effect of Sildenafil Citrate (Viagra) on the Hemodynamics of Exercise Tolerance in Advanced Congestive Heart Failure.
The purpose of this study is to determine if sildenafil (Viagra) improves exercise tolerance.
Patients will undergo an exercise stress test. One dose of Sildenafil will then be given, followed by a one hour rest period. A repeat exercise stress test will then be repeated.
Interventional
Phase 3
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Congestive Heart Failure
Drug: sildenafil
Not Provided
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
40
Same as current
February 2006
Not Provided

Inclusion Criteria:

Age 18 - 75 Ejection fraction <35% Heart failure limited by fatigue and shortness of breath -

Exclusion Criteria:

Inability to exercise. Patients with shortness of breath while resting. Patient requiring intravenous medication. Patients taking the following medications: nitroglycerine pill/patch/paste, isordil and Imdur

Sexes Eligible for Study: All
18 Years to 75 Years   (Adult, Older Adult)
No
Contact information is only displayed when the study is recruiting subjects
United States
 
 
NCT00309816
2001-p-001039
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Massachusetts General Hospital
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Principal Investigator: Marc J Semigran, MD Massachusetts General Hospital
Massachusetts General Hospital
March 2006

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP