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ROSCAP: Reduction of Smoking in Cardiac Patients Study

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT00301626
Recruitment Status : Completed
First Posted : March 13, 2006
Last Update Posted : October 24, 2008
Information provided by:

March 10, 2006
March 13, 2006
October 24, 2008
October 2000
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Smoking reduction
Same as current
Complete list of historical versions of study NCT00301626 on ClinicalTrials.gov Archive Site
Smoking cessation, biomarker measures
Same as current
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ROSCAP: Reduction of Smoking in Cardiac Patients Study
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Background. The ROSCAP Study was a randomized controlled trial in heart disease patients to test the effect of a smoking reduction intervention on cigarettes per day (cpd) and biochemical and clinical indicators of tobacco exposure. .
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Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
  • Nicotine Dependence
  • Tobacco Dependence
  • Cardiac Disease
Behavioral: smoking reduction intervention (including NRT)
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
January 2005
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Inclusion Criteria:

  • smoked at least 15 cigarettes per day and had one of 11 cardiovascular disorders: history of myocardial infarction, coronary artery bypass surgery, angioplasty, stent placement, thrombolytic therapy, angina, arrhythmia, a history of cardiac arrest, greater than 50% coronary artery stenosis by angiography, ischemia on exercise tolerance testing or congestive heart failure, required to confirm that they were unwilling or uninterested in setting a stop smoking date in the next 30 days.

Exclusion Criteria:

  • 1) unstable angina within the past 2 weeks, 2) unstable psychiatric or substance use disorders or 3) contraindications to nicotine replacement therapy (including pregnancy or intention to become pregnant)
Sexes Eligible for Study: All
18 Years to 80 Years   (Adult, Senior)
Contact information is only displayed when the study is recruiting subjects
United States
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National Institutes of Health (NIH)
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Principal Investigator: Anne Joseph, MD, MPH Minneapolis VAMC & University of Minnesota
Minneapolis Veterans Affairs Medical Center
April 2005

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP