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Simvastatin Effect on End Stage Renal Failure Patients Treated by Peritoneal Dialysis

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ClinicalTrials.gov Identifier: NCT00291863
Recruitment Status : Unknown
Verified February 2006 by Federal University of São Paulo.
Recruitment status was:  Recruiting
First Posted : February 15, 2006
Last Update Posted : February 16, 2006
Sponsor:
Information provided by:
Federal University of São Paulo

February 14, 2006
February 15, 2006
February 16, 2006
February 2006
Not Provided
endothelial venodilation
Same as current
Complete list of historical versions of study NCT00291863 on ClinicalTrials.gov Archive Site
  • Inflammation markers (C-reactive protein, IL-6, TNF)
  • Lipoproteins
  • Oxidative stress
Same as current
Not Provided
Not Provided
 
Simvastatin Effect on End Stage Renal Failure Patients Treated by Peritoneal Dialysis
Simvastatin Effect on Endothelium Dependent Venodilation in Chronic Renal Failure Patients Treated by Peritoneal Dialysis
This study will analyse the effect of simvastatin on endothelium dependent venodilation in chronic renal failure patients treated by peritoneal dialysis. The hypothesis is that patients will have a greater endothelium dependent venodilation after four months of simvastatin use.
This study will analyse the effect of simvastatin on endothelium dependent venodilation in chronic renal failure patients treated by peritoneal dialysis. The hypothesis is that patients will have a greater endothelium dependent venodilation after four months of simvastatin use.
Interventional
Phase 4
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double
Primary Purpose: Treatment
  • Renal Failure, End Stage
  • Peritoneal Dialysis
Drug: Simvastatin
Not Provided
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Unknown status
30
Same as current
February 2006
Not Provided

Inclusion Criteria:

  • end stage renal failure
  • peritoneal dialysis
  • LDL cholesterol > 100mg/dL
  • > 18 years and < 80 years

Exclusion Criteria:

  • using statin or nitrate
  • liver disease
  • diabetes mellitus
Sexes Eligible for Study: All
18 Years to 80 Years   (Adult, Older Adult)
No
Contact information is only displayed when the study is recruiting subjects
Brazil
 
 
NCT00291863
0089/04
Not Provided
Not Provided
Not Provided
Not Provided
Federal University of São Paulo
Not Provided
Principal Investigator: Maristela Bohlke, master Federal University of São Paulo
Federal University of São Paulo
February 2006

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP