Early Exposure to Lead and Adult Antisocial Outcomes

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
National Institute of Environmental Health Sciences (NIEHS)
ClinicalTrials.gov Identifier:
NCT00285610
First received: February 1, 2006
Last updated: November 17, 2014
Last verified: November 2014

February 1, 2006
November 17, 2014
November 2001
October 2006   (final data collection date for primary outcome measure)
Lead Exposure and Antisocial Behavior [ Time Frame: Prenatal (1-2 trimester) and postnatal on a quarterly and bi-annual basis (until 6.5 years) ]
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Complete list of historical versions of study NCT00285610 on ClinicalTrials.gov Archive Site
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Early Exposure to Lead and Adult Antisocial Outcomes
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Prior research indicates a link between early lead exposure and risk for delinquent behavior. In this study, we follow a large birth cohort from the Cincinnati Lead Study into early adulthood to determine whether this increased risk persists. Outcome measures include official arrest records, diagnoses of Substance Abuse Disorder and Antisocial Personality Disorder, self-report of delinquent behavior, and a psychopathy scale. Predictors include pre-natal and post-natal blood lead levels. Multivariate statistical methods will control for potential confounders/covariates.
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Observational
Observational Model: Cohort
Time Perspective: Prospective
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Non-Probability Sample
Pregnant women were recruited from four prenatal clinics in Cincinnati, Ohio if they resided in areas of the city with a high concentration of older, lead-contaminated housing
Lead Poisoning
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
225
October 2006
October 2006   (final data collection date for primary outcome measure)

Inclusion Criteria: (1) Part of original CLS birth cohort -

Exclusion Criteria: (1) Moved out of geographic area

Both
18 Years and older   (Adult, Senior)
No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00285610
11261-CP-003
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National Institute of Environmental Health Sciences (NIEHS)
National Institute of Environmental Health Sciences (NIEHS)
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Principal Investigator: M. Douglas Ris, Ph.D. Children's Hospital Medical Center, Cincinnati
National Institute of Environmental Health Sciences (NIEHS)
November 2014

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP