The Prevalence and Clinical Manifestations of Human Metapneumovirus Among Children With Bronchiolitis.

Tracking Information
First Submitted Date	December 13, 2005
First Posted Date	December 14, 2005
Last Update Posted Date	January 3, 2013
Study Start Date	December 2005
Actual Primary Completion Date	March 2006 (Final data collection date for primary outcome measure)
Current Primary Outcome Measures	Not Provided
Original Primary Outcome Measures	Not Provided
Change History	Complete list of historical versions of study NCT00265187 on ClinicalTrials.gov Archive Site
Current Secondary Outcome Measures	Not Provided
Original Secondary Outcome Measures	Not Provided
Current Other Outcome Measures	Not Provided
Original Other Outcome Measures	Not Provided
Descriptive Information
Brief Title	The Prevalence and Clinical Manifestations of Human Metapneumovirus Among Children With Bronchiolitis.
Official Title	The Prevalence and Clinical Manifestations of Human Metapneumovirus Among Children With Bronchiolitis in Northern Israel.
Brief Summary	Sputum specimens will be obtained from children < 2 years of age and processed by different mode for the HMPV, RSV, Pertussis, Influenza A, B, Parainfluenza 1,2,3, Adenovirus. Clinical and epidemiological data will also be obtained.
Detailed Description	The purpose of the study is to asses the various pathogens of bronchiolitis in children and its' clinical manifestations. Prospective study in 3 Medical centers in Northern Israel. Included will be about 200 infants and children < 2 years hospitalized with bronchiolitis. From each child sputum specimen will be obtained and processed for HUMP - PCR, Pertussis - PCR, RSV - ELISA, DFA, PCR, Influenza A, B, Parainfluenza 1,2,3 - DFA, PCR, Adenovirus - DFA. Epidemiological data will be obtained for every child by structured questioner. Clinical data will be daily obtained by scoring system.
Study Type	Observational
Study Design	Observational Model: Cohort; Time Perspective: Prospective
Target Follow-Up Duration	Not Provided
Biospecimen	Not Provided
Sampling Method	Non-Probability Sample
Study Population	Children 0-24 months hospitalized with acute bronchiolitis
Condition	Respiratory Tract Infection; Children
Intervention	Not Provided
Study Groups/Cohorts	Not Provided
Publications *	Not Provided
* Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
Recruitment Information
Recruitment Status	Completed
Actual Enrollment; (submitted: December 13, 2005)	200
Original Enrollment	Same as current
Actual Study Completion Date	March 2006
Actual Primary Completion Date	March 2006 (Final data collection date for primary outcome measure)
Eligibility Criteria	Inclusion Criteria:Age 0-24 months, hospitalized children, - Exclusion Criteria:Previous hospitalization, previous RSV immunization, immunocompromised patient, previous inclusion in this study, inclusion in another study.
Sex/Gender	Sexes Eligible for Study: All
Ages	up to 2 Years (Child)
Accepts Healthy Volunteers	Yes
Contacts	Contact information is only displayed when the study is recruiting subjects
Listed Location Countries	Israel
Removed Location Countries
Administrative Information
NCT Number	NCT00265187
Other Study ID Numbers	3350105
Has Data Monitoring Committee	No
U.S. FDA-regulated Product	Not Provided
IPD Sharing Statement	Not Provided
Responsible Party	Dan Miron, MD, HaEmek Medical Center, Afula, Israel
Study Sponsor	HaEmek Medical Center, Israel
Collaborators	Not Provided
Investigators	Principal Investigator: Dan Miron, MD HaEmek Medicak Center, Afula, Israel
PRS Account	HaEmek Medical Center, Israel
Verification Date	August 2006