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DBT and Escitalopram in Borderline Personality Disorder

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ClinicalTrials.gov Identifier: NCT00255554
Recruitment Status : Unknown
Verified November 2005 by Bronx VA Medical Center.
Recruitment status was:  Recruiting
First Posted : November 21, 2005
Last Update Posted : November 21, 2005
Sponsor:
Information provided by:
Bronx VA Medical Center

November 17, 2005
November 21, 2005
November 21, 2005
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Measures of impulsivity, aggression, affective impulsivity, immediate and delayed memory, and cognitive processing at baseline, 6 months and 9 months
Same as current
No Changes Posted
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DBT and Escitalopram in Borderline Personality Disorder
Effects of Dialectical Behavioral Therapy and Escitalopram on Impulsive Aggression, Affective Instability and Cognitive Processing in Borderline Personality Disorder
Subjects will receive six months of DBT, consisting of one 90-minute group and one 60-minute individual session per week as well as telephone availability of the individual therapist. Half the subjects will concurrently receive escitalopram while half will receive placebo, in a randomized double-blind design.
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Interventional
Not Applicable
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double
Primary Purpose: Treatment
Borderline Personality Disorder
  • Behavioral: Dialectical Behavioral Therapy
  • Drug: Escitalopram
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Unknown status
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Inclusion Criteria: Is a male or female between 18 and 60 who meets criteria for Borderline Personality Disorder and has been off psychotropic medications for at least 2 weeks (6 weeks for fluoxetine).

Exclusion Criteria: Meets criteria for Schizophrenia, Bipolar Disorder, Mental Retardation, current or recent Substance Dependence or a current Major Depressive Episode. Subjects also should not currently be in individual psychotherapy. (Case management and work therapy programs are allowed.)

Sexes Eligible for Study: All
18 Years to 60 Years   (Adult)
No
Contact information is only displayed when the study is recruiting subjects
United States
 
 
NCT00255554
3277-03-0027
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Bronx VA Medical Center
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Principal Investigator: Marianne Goodman, MD Bronx VA Medical Center/Mount Sinai School of Medicine
Bronx VA Medical Center
November 2005

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP