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Employment-based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 2

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Kenneth Silverman, Johns Hopkins University
ClinicalTrials.gov Identifier:
NCT00249457
First received: November 3, 2005
Last updated: September 6, 2016
Last verified: September 2016
History of Changes

November 3, 2005
September 6, 2016
October 1996
January 2006   (final data collection date for primary outcome measure)
Percentage of urine samples at the assessments that were negative for cocaine, opiates, and opiates and cocaine [ Time Frame: every 30 days throughout fourth year ] [ Designated as safety issue: No ]
Percentage of urine samples at the assessments that were negative for cocaine, opiates, and opiates and cocaine
Complete list of historical versions of study NCT00249457 on ClinicalTrials.gov Archive Site
  • HIV risk behaviors [ Time Frame: every 30 days throughout fourth year ] [ Designated as safety issue: No ]
  • Percentage of participants employed each month [ Time Frame: every 30 days throughout fourth year ] [ Designated as safety issue: No ]
  • Number of days employed each month [ Time Frame: every 30 days throughout fourth year ] [ Designated as safety issue: No ]
  • Percentage of participants to self-report abstinence at all time points [ Time Frame: every 30 days throughout fourth year ] [ Designated as safety issue: No ]
  • HIV risk behaviors
  • Percentage of participants employed each month
  • Number of days employed each month
  • Percentage of participants to self-report abstinence at all time points
Not Provided
Not Provided
 
Employment-based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 2
A Therapeutic Workplace for Drug Abusers
The purpose of this study is to determine whether long-term exposure to the Therapeutic Workplace intervention could sustain drug abstinence over an extended period of time in heroin- and cocaine-dependent, unemployed, treatment-resistant young mothers.
The current study is a continuation of the research into the development and evaluation of a novel treatment designed to address the chronic, persistent nature of drug addiction. This treatment, called the Therapeutic Workplace, integrates abstinence reinforcement contingencies of proven efficacy into a model supported work program. Participants were paid to work or to train in the Therapeutic Workplace but had to provide drug-free urine samples to gain daily access. Forty participants were randomly assigned to a Therapeutic Workplace or usual care control group. Therapeutic Workplace participants could work for about 5 years. This study reports the effects of the intervention over a follow-up period of 8 years after treatment initiation.
Interventional
Not Provided
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
  • Behavior, Addictive
  • Cocaine Abuse
  • Cocaine Dependence
  • Heroin Dependence
  • Opioid Dependence
Behavioral: Contingency management
Invited to attend the Therapeutic Workplace 3 hr per day, Monday through Friday. Each day when a participant reported to the workplace, she was required to provide a urine sample. If the sample tested negative for opiates and cocaine, she was allowed to work that day. Participants who gained entrance to the workplace participated in basic skills education and job skills training throughout each 3-hr work shift.
  • Experimental: Therapeutic Workplace
    Contingency management. Invited to work in the Therapeutic Workplace. Completed monthly assessments.
    Intervention: Behavioral: Contingency management
  • No Intervention: Usual Care Control Group
    No intervention. Not invited to work int the Therapeutic Workplace. Completed monthly assessments.
Aklin WM, Wong CJ, Hampton J, Svikis DS, Stitzer ML, Bigelow GE, Silverman K. A therapeutic workplace for the long-term treatment of drug addiction and unemployment: eight-year outcomes of a social business intervention. J Subst Abuse Treat. 2014 Nov-Dec;47(5):329-38. doi: 10.1016/j.jsat.2014.06.013. Epub 2014 Jul 12.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
40
January 2006
January 2006   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • When originally enrolled in the study, participants were at least 18 years old, unemployed, and methadone maintenance patients of the Center for Addiction and Pregnancy (CAP) who continued to use opiates or cocaine during CAP treatment.

Exclusion Criteria:

  • Participants were excluded if they were at risk for suicide at the time of intake or if they had serious psychiatric illness (e.g., schizophrenia).
Female
18 Years to 50 Years   (Adult)
No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00249457
NIDA-13107-2
No
No
The data for this study have been published in a peer-reviewed journal.
Kenneth Silverman, Johns Hopkins University
Johns Hopkins University
Not Provided
Principal Investigator: Kenneth Silverman, Ph.D. Johns Hopkins University
Johns Hopkins University
September 2016

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP