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CPAP Versus Bilevel Pressure Support Ventilation in Cardiogenic Pulmonary Edema

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ClinicalTrials.gov Identifier: NCT00213681
Recruitment Status : Completed
First Posted : September 21, 2005
Last Update Posted : June 18, 2013
Information provided by (Responsible Party):
University Hospital, Rouen

September 14, 2005
September 21, 2005
June 18, 2013
November 2002
Not Provided
Improvement in PaCO2 at the end of ventilation
Same as current
Complete list of historical versions of study NCT00213681 on ClinicalTrials.gov Archive Site
  • Endotracheal intubation, myocardial infarction and mortality during the first 24 hours
  • Duration of the ventilation
  • Blood gases, vital signs
  • Time to transfer to medical ward
  • Time to hospital discharge
  • Easiness to use was evaluated by nurses
  • Patients operational tolerance
  • Complications of each ventilation mode
Same as current
Not Provided
Not Provided
CPAP Versus Bilevel Pressure Support Ventilation in Cardiogenic Pulmonary Edema
CPAP Boussignac Versus Bilevel Pressure Support Ventilation in Severe Acute Cardiogenic Pulmonary Edema
To evaluate whether bilevel positive airway pressure more rapidly improves ventilation than continuous positive airway pressure (CPAP) in patients with acute pulmonary edema. CPAP is delivered via a simple device connected to oxygen.
Not Provided
Phase 3
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Severe Acute Cardiogenic Pulmonary Edema
Device: Boussignac CPAP - bilevel ventilation support
Not Provided
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
Not Provided
March 2005
Not Provided

Inclusion Criteria:

  • age > 16 yrs, acute onset of severe respiratory distress, bilateral rales and typical findings of congestion on chest radiograph
  • breathing frequency of > 30/min, SpO2 >90%, use of accessory respiratory muscles
Sexes Eligible for Study: All
Child, Adult, Senior
Contact information is only displayed when the study is recruiting subjects
Not Provided
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University Hospital, Rouen
University Hospital, Rouen
Not Provided
Principal Investigator: Fabienne MORITZ, MD University Hospital, Rouen
University Hospital, Rouen
June 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP