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Radiation Dosimetry in Teeth

This study has been terminated.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00178347
First Posted: September 15, 2005
Last Update Posted: May 19, 2009
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
University of Rochester
September 12, 2005
September 15, 2005
May 19, 2009
December 2004
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Complete list of historical versions of study NCT00178347 on ClinicalTrials.gov Archive Site
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Radiation Dosimetry in Teeth
Radiation Dosimetry in Teeth

Irradiation of any tissue creates changes in that tissue. Ionizing radiation imparts charges to the tissue as it interacts with tissue components, changing the tissue structure. The specific type of modification also depends to some extent upon the type of tissue irradiated. It has been shown that it is possible to read the tooth enamel irradiation record using techniques such as electron paramagnetic resonance (EPR), or electron spin resonance (ESR).

It is proposed to examine radiation responses in approximately one hundred (100) human teeth. This would include teeth free of, as well as those containing, amalgam (silver) restorations. For the first group, teeth that have already been collected (pre-existing pathological specimens) would be used. These teeth were surgical/pathological discards collected without identifiers by the dental providers.

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Observational
Time Perspective: Retrospective
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Non-Probability Sample
discarded pathological specimen(teeth)
Radiation Tolerance
Radiation: Exposure to irradiation
Treatment for Cancer using Radiation -dose will be the standard of Care for the type of Cancer being treated
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Terminated
10
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Inclusion Criteria:

  • Discarded pathologic specimens (teeth)
Sexes Eligible for Study: All
Child, Adult, Senior
No
Contact information is only displayed when the study is recruiting subjects
United States
 
 
NCT00178347
URCC 11070
No
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Paul Okunieff, University of Rochester, Medical Center
University of Rochester
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Study Chair: Paul Okunieff, MD University of Rochester, Dept. of Radiation Oncology
University of Rochester
May 2009