The Effect of Hibiscus Sabdariffa L. Tea on Blood Pressure

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00175110
Recruitment Status : Completed
First Posted : September 15, 2005
Last Update Posted : December 3, 2009
Celestial Seasonings
Tufts Medical Center
Information provided by:
Tufts University

September 12, 2005
September 15, 2005
December 3, 2009
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December 2007   (Final data collection date for primary outcome measure)
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Complete list of historical versions of study NCT00175110 on Archive Site
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The Effect of Hibiscus Sabdariffa L. Tea on Blood Pressure
The Effect of Hibiscus Sabdariffa L. Tisane on Blood Pressure in Prehypertensive and Mildly Hypertensive Men and Women
The goal of this study is to find out whether the plant compounds present in Hibiscus sabdariffa, a plant commonly used in herbal tea blends and other beverages, will have a beneficial effect on blood pressure in people with mildly elevated blood pressure.
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Phase 1
Phase 2
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Treatment
Behavioral: herbal therapy/botanical therapy (Hibiscus sabdariffa)
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McKay DL, Chen CY, Saltzman E, Blumberg JB. Hibiscus sabdariffa L. tea (tisane) lowers blood pressure in prehypertensive and mildly hypertensive adults. J Nutr. 2010 Feb;140(2):298-303. doi: 10.3945/jn.109.115097. Epub 2009 Dec 16.

*   Includes publications given by the data provider as well as publications identified by Identifier (NCT Number) in Medline.
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December 2007
December 2007   (Final data collection date for primary outcome measure)

Inclusion Criteria:

  • Systolic blood pressure 120-150 mm Hg
  • Diastolic blood pressure 95 mm Hg or less
  • Body mass index (BMI) 18.5-34.9 kg/m2

Exclusion Criteria:

  • Smoking
  • Use of medications that influence blood pressure
  • Cardiovascular disease
  • Chronic kidney disease
  • Diabetes
  • Regular use of vitamin C supplements (min 500 mg/day) within prior 30 days
  • Regular strenuous aerobic activity greater than 30 min/day
  • Excessive intake of caffeine or alcohol
  • Pregnancy within last 6 months or during study period
  • Abnormal complete blood count (CBC), urinalysis or electrocardiogram (EKG)
Sexes Eligible for Study: All
30 Years to 70 Years   (Adult, Senior)
Contact information is only displayed when the study is recruiting subjects
United States
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Jeffrey B. Blumberg, Tufts University
Tufts University
  • Celestial Seasonings
  • Tufts Medical Center
Principal Investigator: Jeffrey B Blumberg, Ph.D. Tufts Medical Center
Tufts University
December 2009

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP