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The Role of CGRPand Nociceptin in Migraine

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ClinicalTrials.gov Identifier: NCT00155129
Recruitment Status : Unknown
Verified June 2005 by National Taiwan University Hospital.
Recruitment status was:  Recruiting
First Posted : September 12, 2005
Last Update Posted : September 12, 2005
Sponsor:
Information provided by:

September 9, 2005
September 12, 2005
September 12, 2005
January 2005
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No Changes Posted
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The Role of CGRPand Nociceptin in Migraine
The Role of Calcitonin Gene-Related Peptide(CGRP)and Nociceptin in the Pathogenesis of Migraine
The release of the neuropeptide calcitonin gene-related peptide (CGRP) is thought to play a causative role in migraine. Nociceptin immunoreactivity and ORL-1 mRNA have been detected in human trigeminal ganglia where it was co-localized with CGRP. It may play a role in migraine pathogenesis. We are collecting the blood samples of migraineurs for analysis of these neuropeptides.
The release of the neuropeptide calcitonin gene-related peptide (CGRP) is thought to play a causative role in migraine. Nociceptin immunoreactivity and ORL-1 mRNA have been detected in human trigeminal ganglia where it was co-localized with CGRP. It may play a role in migraine pathogenesis. We are collecting the blood samples of migraineurs for analysis of these neuropeptides.
Observational
Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Cross-Sectional
Time Perspective: Prospective
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  • Migraine
  • Headache
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Unknown status
200
June 2005
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Inclusion Criteria: patients with headache -

Exclusion Criteria: fever, congenital anomaly, CNS organic lesions

Sexes Eligible for Study: All
3 Years to 50 Years   (Child, Adult)
Yes
Contact information is only displayed when the study is recruiting subjects
Taiwan
 
 
NCT00155129
9361701099
9361701099
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National Taiwan University Hospital
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Principal Investigator: Pi-Chuan Fan Department of Pediatric, NTUH
National Taiwan University Hospital
June 2005