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Impact of nCPAP Treatment on Liver Function in Patients With Sleep Apnea Syndrome and Nonalcoholic Steatohepatitis

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ClinicalTrials.gov Identifier: NCT00152711
Recruitment Status : Unknown
Verified September 2005 by University Hospital, Angers.
Recruitment status was:  Recruiting
First Posted : September 9, 2005
Last Update Posted : February 13, 2007
Sponsor:
Information provided by:
University Hospital, Angers

September 8, 2005
September 9, 2005
February 13, 2007
September 2004
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Complete list of historical versions of study NCT00152711 on ClinicalTrials.gov Archive Site
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Impact of nCPAP Treatment on Liver Function in Patients With Sleep Apnea Syndrome and Nonalcoholic Steatohepatitis
Impact of nCPAP Treatment on Liver Function in Patients With Sleep Apnea Syndrome and Nonalcoholic Steatohepatitis: A Prospective Cross Over Trial
This study aims to evaluate the impact of nasal continuous positive airway pressure (nCPAP) treatment on liver enzymes in patients with sleep apnea syndrome and nonalcoholic steatohepatitis. Using a cross over design, the evolution of liver enzymes will be evaluated in 40 patients during a consecutive period of 6 weeks, with and without nCPAP treatment.
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Interventional
Not Applicable
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
  • Sleep Apnea Syndrome
  • Nonalcoholic Steatohepatitis
Device: nCPAP
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Unknown status
40
Same as current
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Inclusion Criteria:

  • 18 to 70 years old
  • Nonalcoholic steatohepatitis proven by liver biopsy
  • Sleep apnea syndrome proven by polysomnography with an apnea-hypopnea index > 10 events/hour
  • Informed consent

Exclusion Criteria:

  • Psychiatric disorder
  • Other cause of liver disease
  • Professional driver
Sexes Eligible for Study: All
18 Years to 70 Years   (Adult, Older Adult)
No
Contact information is only displayed when the study is recruiting subjects
France
 
 
NCT00152711
PHRC 03-07
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University Hospital, Angers
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Principal Investigator: Frédéric Gagnadoux UH Angers
University Hospital, Angers
September 2005

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP